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Volumn 24, Issue 8, 2001, Pages 930-934
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Transport characteristics of ebastine and its metabolites across human intestinal epithelial Caco-2 cell monolayers
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Author keywords
Caco 2 cell; Cyclosporin A; CYP3A4; Ebastine; Intestinal absorption; P glycoprotein
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Indexed keywords
BUTYROPHENONE DERIVATIVE;
CARBON 14;
CAREBASTINE;
CYCLOSPORIN A;
CYTOCHROME P450 3A4;
DESBUTYROPHENONE;
DRUG METABOLITE;
EBASTINE;
GLYCOPROTEIN P;
HISTAMINE H1 RECEPTOR ANTAGONIST;
TRITIUM;
UNCLASSIFIED DRUG;
APICAL MEMBRANE;
ARTICLE;
BASOLATERAL MEMBRANE;
BINDING AFFINITY;
CELL SECRETION;
CELL STRAIN CACO 2;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DIFFUSION;
DRUG ABSORPTION;
FIRST PASS EFFECT;
HUMAN;
HUMAN CELL;
IN VIVO STUDY;
INHIBITION KINETICS;
INTESTINE ABSORPTION;
INTESTINE EPITHELIUM CELL;
LIPOPHILICITY;
MONOLAYER CULTURE;
PROTEIN EXPRESSION;
TRANSPORT KINETICS;
BIOLOGICAL TRANSPORT, ACTIVE;
BUTYROPHENONES;
CACO-2 CELLS;
CYCLOSPORINE;
HISTAMINE H1 ANTAGONISTS;
HUMANS;
IMMUNOSUPPRESSIVE AGENTS;
P-GLYCOPROTEIN;
PIPERIDINES;
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EID: 0034870523
PISSN: 09186158
EISSN: None
Source Type: Journal
DOI: 10.1248/bpb.24.930 Document Type: Article |
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Times cited : (7)
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References (24)
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