Letters to the editor: Absence of evidence is not evidence of absence - Redundancy blocks determination of cause and effect [1]

Journal of Bone and Mineral Research

Volumn 16, Issue 9, 2001, Pages 1728-1729

  Chenu, C ^a   Itzstein, C ^a   Espenosa, L ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; DIZOCILPINE; GLUTAMATE RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; DIZOCILPINE MALEATE; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYLASPARTIC ACID;

ANIMAL CELL; ANIMAL MODEL; BONE CELL; CELL DIFFERENTIATION; GENE EXPRESSION; KNOCKOUT MOUSE; LETTER; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOLYSIS; SIGNAL TRANSDUCTION; ANIMAL; BONE DEVELOPMENT; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; NOTE; PHYSIOLOGY;

2-AMINO-5-PHOSPHONOVALERATE; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; BONE RESORPTION; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLUTAMIC ACID; N-METHYLASPARTATE; OSTEOBLASTS; OSTEOGENESIS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 0034860641     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.9.1728     Document Type: Letter

References (13)

1. Glutamate does not play a major role in controlling bone growth
2. Mechanically regulated expression of a neural glutamate transporter in bone: A role for excitatory amino acids as osteotropic agents?
3. Glutamate receptors are expressed by bone cells and are involved in bone resorption
4. Expression of N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone
5. Active NMDA glutamate receptors are expressed by mammalian osteoclasts
6. Functional characterization of N-methyl-D-aspartic acid-gated channels in bone cells
7. The glutamate receptor antagonist MK801 modulates bone resorption in vitro by a mechanism predominantly involving osteoclast differentiation
8. Specific antagonists of NMDA receptors prevent osteoclast sealing zone formation required for bone resorption
9. Expression of functional metabotropic glutamate receptors in primary cultured rat osteoblasts
10. Kinetics of osteoprogenitor proliferation and osteoblast differentiation in vitro
11. The NMDA-type glutamate receptor antagonist MK801 regulates differentiation of rat bone marrow osteoprogenitors and influences adipogenesis
12. Molecular identification of NMDA glutamate receptors expressed in bone cells
13. Osteopontin-deficient mice are resistant to ovariectomy-induced bone resorption