Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplantation

Biology of Blood and Marrow Transplantation

Volumn 7, Issue 7, 2001, Pages 368-377

  Panoskaltsis Mortari, Angela ^a   Hermanson, John R ^a   Haddad, Imad Y ^a   Wangensteen, O Douglas ^a   Blazar, Bruce R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Allogeneic BMT; ICAM I; Idiopathic pneumonia syndrome

Indexed keywords

BUFFER; CHEMOKINE; CYCLOPHOSPHAMIDE; CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOTACTIN; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHATE; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

ALLOGENIC BONE MARROW TRANSPLANTATION; ALLOIMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL MIGRATION; COLON; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE SEVERITY; DONOR; DOSE RESPONSE; GRAFT VERSUS HOST REACTION; HOST; IDIOPATHIC DISEASE; LETHALITY; LIVER; LUNG FUNCTION; LUNG WEIGHT; MACROPHAGE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PATHOPHYSIOLOGY; PNEUMONIA; RECIPIENT; REGULATORY MECHANISM; SPLEEN CELL; T LYMPHOCYTE; TISSUE INJURY; TREATMENT OUTCOME; WHOLE BODY RADIATION;

EID: 0034858367     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1053/bbmt.2001.v7.pm11529486     Document Type: Article

References (57)

1. Idiopathic pneumonia syndrome after bone marrow transplantation
2. The effect of donor T lymphocytes and total-body irradiation on hemopoietic engraftment and pulmonary toxicity following experimental allogeneic bone marrow transplantation
3. The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide
4. Keratinocyte growth factor (KGF) given before conditioning decreases B7 ligand and granzyme B expression in situ and hastens lung repair post-allogeneic bone marrow transplantation (BMT) in mice
5. High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells: A potential mechanism of injury after marrow transplantation
6. Induction of monocyte- and T cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome (IPS) following allogeneic murine bone marrow transplantation (BMT)
7. Chemokines
8. Lymphocyte trafficking and regional immunity
9. Chemokines trigger immediate β2 integrin affinity and mobility changes: Differential regulation and roles in lymphocyte arrest under flow
10. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
11. Regulation and function of adhesion molecule expression by human alveolar epithelial cells
12. Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1
13. ICAM-1 and B7-1 provide similar but distinct costimulation for CD8+ T cells, while CD4+ T cells are poorly costimulated byICAM-1
14. Intercellular adhesion molecule 1 is critical for activation of CD28-deficient T cells
15. ICAM-1 deficiency suppresses host allosensitization and rejection of MHC-disparate corneal transplants
16. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1
17. Coblockade of the LFA:ICAM and CD 28/CTLA-4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts
18. Expression of adhesion molecules in human intestinal graft-versus-host disease
19. The immunopathology of upper gastrointestinal acute graft-versus-host disease. Lymphoid cells and endothelial adhesion molecules
20. Liver T cell subsets and adhesion molecules in murine graft-versus-host disease
21. Reduction in the severity of graft-versus-host disease and increased survival in allogeneic mice by treatment with MoAb antibodies to cell adhesion antigens LFA-1 alpha and MALA-2
22. Amelioration of graft versus host disease with anti-ICAM-1 therapy
23. Role of intercellular adhesion molecule-1 and lymphocyte function associated antigen-1 during non-suppurative destructive cholangitis in a mouse graft-versus-host disease model
24. Temporal correlation of tumor necrosis factor-alpha release, upregulation of pulmonary ICAM-1 and VCAM-1, neutrophil sequestration, and lung injury in diet-induced pancreatitis
25. Intercellular adhesion molecule 1 knockout abrogates radiation induced pulmonary inflammation
26. Effect of ICAM-1 blockade on lung inflammation and physiology during acute viral bronchiolitis in rats
27. ICAM-1 mediates lung leukocyte recruitment but not pulmonary fibrosis in a murine model of bleomycin-induced lung injury
28. Roles of ICAM-1 for abnormal leukocyte recruitment in the microcirculation of bleomycin-induced fibrotic lung injury
29. Role of P-selectin and ICAM-1 in pancreatitis-induced lung inflammation in rats: Significance of oxidative stress
30. P-selectin and ICAM-1 mediate endotoxin-induced neutrophil recruitment and injury to the lung and liver
31. Blockade of leucocyte function-associated antigen-1 (LFA-1) decreases lymphocyte trapping in the normal pulmonary vasculature: Studies in the isolated buffer-perfused rat lung
32. Adherence of adoptively transferred alloreactive Th1 cells in lung: Partial dependence on LFA-1 and ICAM-1
33. In vivo blockade of CD28/CTLA4: B7/BB1 interaction with CTLA4-Ig reduces lethal murine graft-versus-host disease across the major histocompatibility complex barrier in mice
34. Nonmitogenic anti-CD3F(ab′)2 fragments inhibit lethal murine graft-versus-host disease induced across the major histocompatibility barrier
35. Engraftment of severe combined immune deficient (SCID) mice given allogeneic bone marrow (BM) via in utero or post-natal transfer
36. Solute conductance of blood-gas barrier in hamsters exposed to hyperoxia
37. Bleomycin-induced changes in pulmonary microvascular albumin permeability and extravascular albumin space
38. Pressure-volume curves of air- and liquid-filled excised lungs-surface tension in situ
39. Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension
40. Expression of pulmonary mRNA encoding ICAM-1, VCAM-1, and P-selectin following thoracic irradiation in mice
41. Migration of activated CD8+ T lymphocytes to sites of viral infection does not require endothelial selectins
42. Cross-linking of ICAM-1 induces co-signaling of an oxidative burst from mononuclear leukocytes
43. Mac-1 (CD11b/CD18) mediates adherence-dependent hydrogen peroxide production by human and canine neutrophils
44. Tumor necrosis factor up-regulates intercellular adhesion molecule 1, which is important in the neutrophil-dependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat
45. The accumulation of dendritic cells in the lung is impaired in CD18-/- but not in ICAM-1-/- mutant mice
46. Blood monocyte migration to acute lung inflammation involves both CD11/CD18 and very late activation antigen-4-dependent and independent pathways
47. Monocyte migration through the alveolar epithelial barrier: Adhesion molecule mechanisms and impact of chemokines
48. Activation of peripheral blood T cells by interaction and migration through endothelium: Role of lymphocyte function antigen-1/intercellular adhesion molecule-1 and interleukin-15
49. Cross-linking of LFA-1 induces secretion of macrophage inflammatory protein (MIP)-1α and MIP-1β with consequent directed migration of activated lymphocytes
50. + T cells to the liver, lung and spleen during graft-versus-host disease
51. Intercellular adhesion molecule-1 mediates the expression on monocyte-derived MIP-1α during monocyte-endothelial cell interactions
52. Macrophage/fibroblast coculture induces macrophage inflammatory protein-1α production mediated by intercellular adhesion molecule-1 and oxygen radicals
53. Blocking pulmonary ICAM-1 expression ameliorates lung injury in established diet-induced pancreatitis
54. Antibody to intercellular adhesion molecule-1 (CD54) decreases survival and not lung injury in baboons with sepsis
55. Pro-inflammatory cytokines increase in sepsis after anti-adhesion molecule therapy
56. Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice
57. Susceptibility to local and systemic bacterial infections in intercellular adhesion molecule-1 deficient transgenic