Intramuscular injection of insulin lispro or soluble human insulin: Pharmacokinetics and glucodynamics in Type 2 diabetes

Diabetic Medicine

Volumn 18, Issue 7, 2001, Pages 562-566

  Milicevic, Z ^a,b   Profozic, V ^a   Wyatt, J ^b   Ristic, S ^b   Woodworth, J R ^b   Seger, M ^b   Kaliterna, D ^a   Bates, P ^b   Metelko, Z ^a  

^a University of Zagreb   (Croatia)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

Glucodynamic; Insulin lispro; Intramuscular injection; Pharmacokinetic

Indexed keywords

GLIBENCLAMIDE; HUMAN INSULIN; INSULIN LISPRO; ISOPHANE INSULIN; SULFONYLUREA;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG METABOLISM; GLUCOSE CLAMP TECHNIQUE; GLUCOSE INFUSION; HUMAN; INSULIN BLOOD LEVEL; NON INSULIN DEPENDENT DIABETES MELLITUS; PHARMACODYNAMICS; PHARMACOKINETICS; RANDOMIZED CONTROLLED TRIAL; TREATMENT FAILURE;

BLOOD GLUCOSE; BODY MASS INDEX; CROSS-OVER STUDIES; DIABETES MELLITUS, TYPE 2; GLYBURIDE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; INJECTIONS, INTRAMUSCULAR; INSULIN; LEAST-SQUARES ANALYSIS; MIDDLE AGED;

EID: 0034856102     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.2001.00522.x     Document Type: Article

References (21)

1. Insulin lispro
2. Restoration of early rise in plasma insulin levels improves the glucose tolerance of type 2 diabetic patients
3. Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes
4. Biphasic insulin response to high glucose and a role of protons and calcium
5. The mechanism of insulin secretion
6. Loss of the first phase insulin response to intravenous glucose in subjects with persistent impaired glucose tolerance
7. Impaired fasting glucose is not a risk factor for atherosclerosis
8. Risk factors for myocardial infarction and death in newly detected NIDDM: The Diabetes Intervention Study, 11-year follow-up
9. Relationship of glucose and insulin levels to the risk of myocardial infarction: A case-control study
10. Action profiles of fast onset insulin analogues
11. Where do lean diabetics inject their insulin?
12. Subcutaneous or intramuscular injections of insulin in children
13. Protein delivery with infusion pumps
14. Intramuscular versus subcutaneous injection of soluble and insulin lispro: Comparison of metabolic effects in healthy subjects
15. Variation in absorption of NPH insulin due to intramuscular injection
16. Relationship between absorption of radiolabeled soluble insulin, subcutaneous blood flow, and anthropometry
17. Injection site effects on the pharmacokinetics and glucodynamics of insulin lispro and regular insulin
18. Time-action profile of the intermediate-acting insulin analogue des(64,65)-human proinsulin
19. Standardization of glycohemoglobin determinations in the clinical laboratory: 3 Years of experience
20. Humalog, a rapidly absorbed analog of insulin, determined with Coat-a-Count insulin radioimmunoassay
21. Mechanisms of the kinetic defect in insulin action in obesity and NIDDM