High-dose stabilized chlorite matrix WF10 prolongs cardiac xenograft survival in the hamster-to-rat model without inducing utrastructural or biochemical signs of cardiotoxicity

Pharmacology and Toxicology

Volumn 89, Issue 2, 2001, Pages 92-95

  Hansen, Alastair ^a   Kemp, Kåre ^a   Kemp, Ejvind ^b   Bouchelouche, Kirsten ^a   Bouchelouche, Pierre ^c   Dieperink, Hans ^b   Horn, Thomas ^a   Larsen, Svend ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b ODENSE UNIVERSITY HOSPITAL   (Denmark)

^c KØGE HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CREATINE KINASE MB; MYOGLOBIN; SODIUM CHLORITE; TETRACHLORODECAOXIDE; TROPONIN I; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DRUG MEGADOSE; DRUG STABILITY; GRAFT REJECTION; GRAFT SURVIVAL; HAMSTER; HEART GRAFT; HEART TRANSPLANTATION; HISTOPATHOLOGY; IMMUNOSUPPRESSIVE TREATMENT; NONHUMAN; PRIORITY JOURNAL; RAT; ULTRASTRUCTURE; XENOTRANSPLANTATION;

ANIMALIA; CRICETINAE;

EID: 0034853289     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0773.2001.d01-141.x     Document Type: Article

References (24)

1. Multicenter clinical and analytical evaluation of the AxSYM troponin I immunoassay to assist in the diagnosis of myocardial infarction
2. Comparison of the diagnostic value of cardiac troponin I and T determinations for detecting early myocardial damage and the relationship with histological findings after isoprenaline-induced cardiac injury in rats
3. The role of endomyocardial biopsy in the diagnosis and treatment of heart disease
4. Cardiac troponin. How specific is specific?
5. Changes in concentrations of tissue free radical marker and serum creatine kinase during the post-exercise period in rats
6. Biochemical and ultrastructural indices of muscle damage after a twenty-one kilometer run
7. Rationale for and results from a randomized double-blind trial of tetrachlorodecaoxygen anion complex in wound healing
8. WF10 in xenotransplantation - A potential new approach
9. The impact of ischemia/reperfusion injury on specific and non-specific early and late chronic events after organ transplantation
10. Histopathology of kidney xenograft rejection
11. Equivalent early sensitivities of myoglobin, creatine kinase MB mass, creatine kinase isoform ratios, and cardiac troponins I and T for acure myocardial infarction
12. Effect of WF10 (TCDO) on antigen presentation
13. Balanced macrophage activation hypothesis: A biological model for development of drugs targeted at macrophage functional states
14. Ultrastructural analysis of concordant and disconcordant cardiac xenografts in unmodified recipients
15. Immunosuppressive drug-induced toxicities compromising the half-life of renal allografts
16. Randomized, double-blind, placebo controlled trial of the immune modulator WF10 in patients with advanced AIDS
17. An improved procedure for creatine phosphokinase determination
18. Histopathology of cardiac xenograft rejection
19. Creatine kinase release from regenerated muscles after eccentric contractions in rats
20. Elevated serum cardiac markers in asymptomatic marathon runners after competition: Is the myocardium stunned?
21. Elevations of cardiac troponin I associated with myocarditis. Experimental and clinical correlates
22. Anti-CD4 monoclonal antibody treatment in hamster-to-rat cardiac transplantation. I. Analysis of lymphocyte subsets and anti-donor xenoantibodies
23. Analysis of creatine kinase, CK-MB, myoglobin, and troponin T time-activity curves for early assessment of coronary artery reperfusion after intravenous thrombolysis
24. Effects of ischemia on skeletal muscle energy metabolism in mice lacking creatine kinase monitored by in vivo 31P nuclear magnetic resonance spectroscopy