X-ray-induced chromosome aberrations in human lymphocytes in vitro are potentiated under simulated microgravity conditions (clinostat)

Physica Medica

Volumn 17, Issue SUPPL. 1, 2001, Pages 264-266

  Mosesso, P ^a   Schuber, M ^a   Seibt, D ^a   Schmitz, C ^a   Fiore, M ^a   Schinoppi, A ^a   Penna, S ^a   Palitti, F ^a  

^a UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Ara C; Chromosome aberrations; Inhibitors of DNA repair; Simulated microgravity

Indexed keywords

CYTARABINE;

CELL CYCLE G0 PHASE; CHROMATIN STRUCTURE; CHROMOSOME ABERRATION; CONFERENCE PAPER; CONTROLLED STUDY; EXCISION REPAIR; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE; MICROGRAVITY; SIMULATION; WEIGHTLESSNESS; X RAY;

ANTIMETABOLITES, ANTINEOPLASTIC; CELL DIVISION; CELLS, CULTURED; CHROMOSOME ABERRATIONS; CYTARABINE; DNA REPAIR; G0 PHASE; HUMANS; LYMPHOCYTES; ROTATION; WEIGHTLESSNESS SIMULATION; X-RAYS;

ARA;

EID: 0034852873     PISSN: 11201797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (10)

1. Effect of simulated microgravity conditions on radiation-induced chromosome aberrations and DNA repair in human lymphocytes
2. Evaluation of bleomycin-induced chromosome aberrations under simulated microgravity conditions in human lymphocytes using FISH techniques
3. Conversion of excision repairable DNA lesions to micronuclei within one cell cycle in human lymphocytes
4. Chromosom with high gene density are preferentially repaired in human cells
5. 0-g conditions in laboratory experiments: The important parameters and limitations
6. New Giemsa method for the differentia staining of sister chromatid exchange
7. DNA repair and chromosome aberrations: The effect of cytosine arabinoside on the frequency of chromosome aberrations induced by radiation and chemicals
8. Kinetics of the effect of ara-C on chromosome aberration yield in irradiated human-lymphocytes
9. The nature of DNA lesions that lead to chromosomal aberrations induced by ionising radiation
10. The role of short-lived DNA lesions in the production of chromosome exchange aberrations