Antioxidants in critical care medicine

Environmental Toxicology and Pharmacology

Volumn 10, Issue 4, 2001, Pages 183-188

  Coleman, N A ^a  

^a UNIVERSITY HOSPITALS OF NORTH MIDLANDS NHS TRUST   (United Kingdom)

Author keywords

Acute respiratory distress syndrome; Antioxidant; Selenium

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CALCIUM CHANNEL BLOCKING AGENT; GLUTAMINE; LAZAROID; MANNITOL; METHYLPREDNISOLONE; NIMODIPINE; PHENYTOIN; REACTIVE OXYGEN METABOLITE; SCAVENGER; SELENIUM; TIRILAZAD;

ADULT RESPIRATORY DISTRESS SYNDROME; ANTIOXIDANT ACTIVITY; BRAIN HYPOXIA; BRAIN INJURY; CELL DAMAGE; CONTROLLED STUDY; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; INTENSIVE CARE; MAJOR CLINICAL STUDY; MORTALITY; MULTIPLE ORGAN FAILURE; NEUROLOGIC DISEASE; OUTCOMES RESEARCH; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PATIENT CARE; POPULATION; PRIORITY JOURNAL; REVIEW; SPINAL CORD INJURY; SUBARACHNOID HEMORRHAGE; SURVIVAL;

EID: 0034852789     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1382-6689(01)00082-5     Document Type: Article

References (38)

1. Selenium replacement in patients with severe systemic inflammatory response syndrome improves clinical outcome
2. A trial of antioxidants N-acetylcysteine and procysteine in ARDS
3. Methylprednisolone or naloxone treatment after acute spinal cord injury: 1 year follow up data. Results of the second National Acute Spinal Cord Injury Study
4. Administration of methylprednisolone for 24 or 48 hrs or tirilazad mesylate for 48 hrs in the treatment of acute spinal cord injury: Results of the 3rd national acute spinal cord injury randomised controlled clinical trial
5. Plasma antioxidant potential in severe sepsis: A comparison of survivors and non-survivors
6. Effect of 21 Aminosteroid on extracellular energy-related metabolites and amino acids after compression injury of rat spinal cord
7. Calcium antagonists for aneurysmal subarachnoid haemorrhage
8. Induction of tirilazad clearance by phenytoin
9. Selenium, systemic immune response syndrome, sepsis, and outcome in critically ill patients
10. A trial of goal-orientated haemodynamic therapy in critically ill patients
11. A randomised double blind vehicle controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid haemorrhage: A co-operative study in North America
12. Effects of the 21 Aminosteroid U 74006 on experimental head injury in mice
13. The 21 Aminosteroid lipid peroxidase inhibitor U 74006F protects against cerebral ischaemia in gerbils
14. Blocking weight-induced spinal cord injury in rats: Therapeutic effect of the 21 Aminosteroid U-74006F
15. Mitigating increased severity of illness in trauma patients
16. Effect of age and gender on tirilazad pharmacokinetics in humans
17. Antioxidant treatment with N-acetylcysteine during ARDS: A prospective randomised, placebo controlled study
18. Randomised double-blind vehicle controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid haemorrhage: A co-operative study in Europe, Australia and New Zealand
19. Gastric intramucosal pH driven resuscitation and antioxidants: Normalised pH is associated with high survival
20. Ischaemia reperfusion injury in the critically ill: A progenitor of multiple organ failure
21. Double blind randomised, vehicle controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid haemorrhage. Part 2. A co-operative study in North America
22. Double blind randomised, vehicle controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid haemorrhage. Part 1. A co-operative study in Europe, Australia, New Zealand and South Africa
23. Oxidant-antioxidant balance in granulocytes during ARDS
24. Measures of total free radical activity in critically ill patients
25. A multi-centre trial on the efficacy of using tirilazad mesylate in cases of head injury
26. Effect of the 21 Aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischaemia
27. Conference summary: Acute lung injury
28. The novel 21 Aminosteroid U74006F attenuates cerebral oedema and improves survival after brain injury in the rat
29. Antioxidant status in patients with acute respiratory distress syndrome
30. The effect of glutathione and N-acetylcysteine on lipoperoxidative damage in patients with early septic shock
31. Tirilazad mesylate protects vitamin C and E in brain ischaemia reperfusion injury
32. Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage
33. Total vitamin C, ascorbic acid and dehydroascorbic acid concentrations in plasma of critically ill patients
34. N-acetylcysteine enhances recovery from acute lung injury in man: A randomised, double-blind, placebo-controlled study
35. Oxidative metabolism of circulating granulocytes in ARDS
36. Antioxidant therapy in critical care medicine
37. A randomised trial of tirilazad mesylate in patients with acute stroke
38. High dose tirilazad for acute stroke