Why are some meta-analyses more credible than others?

Drug Information Journal

Volumn 35, Issue 3, 2001, Pages 1019-1030

  Koch, A ^a   Rohmel J ^a  

^a Bundesinstitut für Arzenimittel   (Germany)

Author keywords

Clinical trials; Drug regulation; International Conference on Harmonization E9; Meta analysis

Indexed keywords

HEPARIN DERIVATIVE; HIRUDIN; OMEPRAZOLE;

ARTICLE; CLINICAL TRIAL; DRUG COMPARISON; DRUG EFFICACY; DRUG INFORMATION; DRUG SAFETY; DYSPEPSIA; EVALUATION; HUMAN; META ANALYSIS; METHODOLOGY; PRIORITY JOURNAL; RELIABILITY;

EID: 0034851449     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: 10.1177/009286150103500341     Document Type: Article

References (23)

1. Meta-analysis of clinical trials: Summary of an international conference
2. Meta-analysis: Statistical alchemy for the 21st century
3. Meta-analysis and its problems
4. Predictive ability of meta-analyses of randomized controlled trials
5. Editorial: The promise and problems of meta-analysis
6. Letter: Megatrials for clinical decision making
7. "The challenge of meta-analysis": Discussion. Indications and contra-indications for meta-analysis
8. Misleading meta-analysis: Lessons from "an effective, safe, simple" intervention that wasn't
9. Discrepancies between meta-analyses and subsequent large randomized controlled trials
10. Randomized clinical trials
11. Obtaining data from randomised controlled trials: How much do we need for reliable and informative meta-analyses?
12. A Monte Carlo investigation of homogeneity tests of the odds ratio under various sample size configurations
13. A method for assessing the quality of a randomized control trial
14. Rating the quality of evidence for clinical practice guidelines
15. Reporting on methods in clinical trials
16. The procedure of new drug application and the philosophy of critical rationalism or the limits of quality assurance with good clinical practice
17. One large, well-designed, multicenter study as an alternative to the usual FDA paradigm
18. Efficacy of omeprazole in functional dyspepsia: Double-blind, randomized, placebo-controlled trials (the bond and opera studies)
19. Controversies in meta-analysis: The case of the trials of serum cholesterol reduction
20. Comparison of the effects of two doses of recombinant hirudin compared with heparin in patients with acute myocardial ischemia without ST elevation - A pilot study
21. Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularisation procedures in patients with actue myocadial ischemia without ST elecation: A randomised trial