Receptor binding transforms the surface subunit of the mammalian C-type retrovirus envelope protein from an inhibitor to an activator of fusion

Journal of Virology

Volumn 75, Issue 19, 2001, Pages 9096-9105

  Barnett, A L ^a   Cunningham, J M ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROPOIETIN; VIRUS ENVELOPE PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CULTURE MEDIUM; FIBROBLAST; MEMBRANE FUSION; MURINE LEUKEMIA VIRUS; NONHUMAN; PLASMID; PRIORITY JOURNAL; RECEPTOR BINDING; RETROVIRUS; XENOPUS;

ANIMALS; GENE PRODUCTS, ENV; LEUKEMIA VIRUS, MURINE; MICE; RECEPTORS, VIRUS; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 0034849671     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.19.9096-9105.2001     Document Type: Article

References (50)

1. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection
2. Identification of a cellular cofactor required for infection by feline leukemia virus
3. Functional dissection of the Moloney murine leukemia virus envelope protein gp70
4. Modular organization of the Friend murine leukemia virus envelope protein underlies the mechanism of infection
5. Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia viruses
6. Receptor-binding domain of murine leukemia virus envelope glycoproteins
7. A human cell-surface receptor for xenotropic and polytropic murine leukemia viruses: Possible role in G protein-coupled signal transduction
8. Targeting retroviral vectors to CD34-expressing cells: Binding to CD34 does not catalyze virus-cell fusion
9. Structure of influenza hemagglutinin at the pH of membrane fusion
10. Influenza hemagglutinin is spring-loaded by a metastable native conformation
11. Core structure of gp41 from the HIV envelope glycoprotein
12. In vitro binding of purified murine ecotropic retrovirus envelope surface protein to its receptor, MCAT-1
13. Identification of a receptor-binding pocket on the envelope protein of Friend murine leukemia virus
14. Evidence that a precursor glycoprotein is cleaved to yield the major glycoprotein of avian tumor virus
15. Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolution
16. Retrovirus envelope domain at 1.7 angstroms resolution
17. Feline leukemia virus envelope sequences that affect T-cell tropism and syncytium formation are not part of known receptor-binding domains
18. Fv-4 resistance gene: A truncated endogenous murine leukemia virus with ecotropic interference properties
19. Cell fusion induced by the murine leukemia virus envelope glycoprotein
20. The hypervariable domain of the murine leukemia virus surface protein tolerates large insertions and deletions, enabling development of a retroviral particle display system
21. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor
22. Activation of membrane fusion by murine leukemia viruses is controlled in cis or in trans by interactions between the receptor-binding domain and a conserved disulfide loop of the carboxy terminus of the surface glycoprotein
23. A proline-rich motif downstream of the receptor binding domain modulates conformation and fusogenicity of murine retroviral envelopes
24. Activation of a cell entry pathway common to type C mammalian retroviruses by soluble envelope fragments
25. Transgenic Fv-4 mice resistant to Friend virus
26. Construction and use of a safe and efficient amphotropic packaging cell line
27. The pH independence of mammalian retrovirus infection
28. Cloning of the cellular receptor for amphotropic murine retroviruses reveals homology to that for gibbon ape leukemia virus
29. Retroviral entry mediated by receptor priming and low pH triggering of an envelope glycoprotein
30. Processing of the env gene products of Moloney murine leukemia virus
31. Fv-4: Gene controlling resistance to NB-tropic Friend murine leukemia virus. Distribution in wild mice, introduction into genetic background of BALB/c mice, and mapping of chromosomes
32. Second-site changes affect viability of amphotropic/ecotropic chimeric enveloped murine leukemia viruses
33. SU
34. Molecular cloning of a feline leukemia virus that induces fatal immunodeficiency disease in cats
35. Characterization of chimeras between the ecotropic and amphotropic 4070A envelope proteins
36. Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymes
37. Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein
38. Evolution of feline leukemia virus variant genomes with insertions, deletions, and defective envelope genes in infected cats with tumors
39. In vivo evolution of a novel, syncytium-inducing and cytopathic feline leukemia virus variant
40. Retrovirus receptors
41. A transient three-plasmid expression system for the production of high titer retroviral vectors
42. Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses
43. A human amphotropic retrovirus receptor is a second member of the gibbon ape leukemia virus receptor family
44. Structural basis for membrane fusion by enveloped viruses
45. Atomic structure of the ectodomain from HIV-1 gp41
46. The structure of the hemagglutinin membrane glycoprotein of influenza virus
47. Relationship of retrovirus polyprotein cleavages to virion maturation studied with temperature-sensitive murine leukemia virus mutants
48. Structure of the murine leukemia virus envelope glycoprotein precursor
49. Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmcl
50. Identification of the block in targeted retroviral mediated gene transfer