Somatic mutations in MEN type 1 tumors, consistent with the Knudson "two-hit" hypothesis

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 9, 2001, Pages 4371-4374

  Pannett, A A J ^a   Thakker, R V ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; METHIONINE;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CENTROMERE; CHROMOSOME 11Q; CLINICAL ARTICLE; FEMALE; FRAMESHIFT MUTATION; GENE DELETION; GENE LOCATION; GENETIC MARKER; HETEROZYGOSITY LOSS; HUMAN; HYPOPHYSIS TUMOR; HYPOTHESIS; INSULINOMA; KNUDSON TWO HIT HYPOTHESIS; LIPOMA; MALE; MEN1 GENE; MISSENSE MUTATION; MULTIPLE ENDOCRINE NEOPLASIA; PANCREAS ISLET CELL TUMOR; PARATHYROID TUMOR; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SOMATIC MUTATION; TELOMERE; TUMOR SUPPRESSOR GENE;

ADULT; CHROMOSOMES, HUMAN, PAIR 11; DNA; EXONS; FEMALE; GENE DELETION; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE REPEATS; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; MUTATION; POLYMORPHISM, GENETIC;

EID: 0034846922     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.86.9.4371     Document Type: Article

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