Tumor suppressor p53 response is blunted by low-dose-rate radiation

Physica Medica

Volumn 17, Issue SUPPL. 1, 2001, Pages 215-216

  Ohnishi, T ^a   Takahashi, A ^a   Ohnishi, K ^a   Yonezawa, M ^a  

^a NARA MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Bax; p53; Radioadaptation

Indexed keywords

PROTEIN P53;

APOPTOSIS; CONFERENCE PAPER; CONTROLLED STUDY; COSMIC RADIATION; COSMONAUT; GAMMA RADIATION; HUMAN; HUMAN CELL; LONG TERM EXPOSURE; PROTEIN STABILITY; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CARCINOMA, SQUAMOUS CELL; DOSE-RESPONSE RELATIONSHIP, RADIATION; GAMMA RAYS; HUMANS; MICE; MICE, INBRED STRAINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RADIATION TOLERANCE; SIGNAL TRANSDUCTION; SPLEEN; TUMOR SUPPRESSOR PROTEIN P53; X-RAYS;

EID: 0034846468     PISSN: 11201797     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (7)

1. p53-dependent signal transduction induced by stress
2. p53 accumulation in various organs of rats after whole-body exposure to low-dose X-ray irradiation
3. p53 accumulation in the organs of low-dose X-ray-irradiated mice
4. Low-dose-rate radiation attenuates the response of the tumor suppressor TP53
5. Radioadaptation for gene mutation and the possible molecular mechanisms of the adaptive response
6. Modulation of gene expression in Syrian hamster embryo cells following ionizing radiation
7. Regulation of the sequence-specific DNA binding function of p53 by protein kinase C and protein phosphatases