Design, synthesis and properties of synthetic chlorophyll proteins

European Journal of Biochemistry

Volumn 268, Issue 11, 2001, Pages 3284-3295

  Rau, Harald K ^a,c   Snigula, Heike ^d   Struck, Andreas ^b,c   Robert, Bruno ^e   Scheer, Hugo ^d   Haehnel, Wolfgang ^c  

^a Graffinity Pharmaceutical Design GmbH   (Germany)

^b SPX Valley Forge   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e CEA SACLAY   (France)

Author keywords

Chlorophylls; Protein design; Synthetic proteins

Indexed keywords

ALDEHYDE; CHLOROPHYLL; CYSTEINE; LYSINE; OXIME; PHEOPHORBIDE; SULFIDE; ZINC DERIVATIVE;

ARTICLE; CIRCULAR DICHROISM; GEL PERMEATION CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RAMAN SPECTROMETRY; SPECTROSCOPY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; CHLOROPHYLL; CHROMATOGRAPHY, GEL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; DRUG DESIGN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PLANT PROTEINS; SPECTROPHOTOMETRY; SPECTRUM ANALYSIS, RAMAN;

EID: 0034845940     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02231.x     Document Type: Article

References (78)

1. Structure of a bacteriochlorophyll a - Protein from Prosthecochloris aestuarii
2. Structure and X-ray amino-acid sequence of a bacteriochlorophyll alpha protein from Prosthecochloris aestuarii refined at 1.9 Å resolution
3. Structural basis of light harvesting by carotenoids: Peridinin-chlorophyll-protein from Amphidinium carterae
4. Crystal structure of an integral membrane light-harvesting complex from photosynthetic bacteria
5. Atomic model of plant light-harvesting complex by electron crystallography
6. X-ray structure analysis of a membrane protein complex. Electron density map at 3 Å resolution and a model of the chromophores of the photosynthetic reaction center from Rhodopseudomonas viridis
7. 2+) interactions
8. Photosystem I at 4 Å resolution represents the first structural model of a joint photosynthetic reaction centre and core antenna system
9. K′, in an improved electron density map of photosystem I at 4-Å resolution
10. Pigment-pigment interactions and energy transfer in the antenna complex of the photosynthetic bacterium Rhodopseudomonas acidophila
11. Reconstitution of chlorophyll a/b light-harvesting complexes - Xanthophyll-dependent assembly and energy-transfer
12. Pigments induce folding of light-harvesting chlorophyll a/b-binding protein
13. Chlorophyll binding to monomeric light-harvesting complex
14. Mutational analysis of a higher plant antenna protein provides identification of chromophores bound into multiple sites
15. Pigment complexes of light-harvesting chlorophyll a/b binding protein are stabilized by a segment in the carboxyterminal hydrophilic domain of the protein
16. Chlorophyll a/b-binding proteins
17. Carotenoid-binding sites of the major light-harvesting complex II of higher plants
18. Protein engineering of bacterial light-harvesting complexes
19. Protein structure modelling of the bacterial light-harvesting complex
20. Enzymatic and chemical cleavage of the core light-harvesting polypeptides of photosynthetic bacteria: Determination of the minimal polypeptide size and structure required for subunit and light-harvesting complex formation
21. Functions of conserved tryptophan residues of the core light-harvesting complex of Rhodobacter sphaeroides
22. Evaluation of structure-function relationships in the core light-harvesting complex of photosynthetic bacteria by reconstitution with mutant polypeptides
23. Reconstitution of core light-harvesting complexes of photosynthetic bacteria using chemically synthesized polypeptides. 1. Minimal requirements for subunit formation
24. Minimal requirements for in vitro reconstitution of the structural subunit of light-harvesting complexes of photosynthetic bacteria
25. Reconstitution of core light-harvesting complexes of photosynthetic bacteria using chemically synthesized polypeptides. 2. Determination of structural features that stabilize complex formation and their implications for the structure of the subunit complex
26. Structure-function relationships in core light-harvesting complexes (LHI) as determined by characterization of the structural subunit and by reconstitution experiments
27. Chlorophyll binding to peptide maquettes containing a retention motif
28. Bacterial reaction centers with modified tetrapyrrole chromophores
29. Spectroscopic analysis of genetically modified photosynthetic reaction centers PCC 6803 Photosystem I-less background
30. Mutation of chlorophyll ligands in the chlorophyll-binding CP47 protein as studied in a Synechocystis
31. The pathway, kinetics and thermodynamics of electron transfer in wild type and mutant reaction centers of purple nonsulfur bacteria
32. Crystallographic analyses of site-directed mutants of the photosynthetic reaction center from Rhodobacter sphaeroides
33. Mg coordination by amino acid side chains is not required for assembly and function of the special pair in bacterial photosynthetic reaction centers
34. Discovery of natural photosynthesis using Zn-containing bacteriochlrophyll in an aerobic bacterium Acidiphilium rubrum
35. Chlorophyll synthetase can not synthesize chlorophyll a′
36. Reconstitution of the B800 bacteriochlorophylls in the peripheral light harvesting complex B800-850 of Rhodobacter sphaeroides 2.4.1 with Bchl a′ and modified (bacterio-)chlorophylls
37. Exchanging cofactors in the core antennae from purple bacteria: Structure and properties of Zn-bacteriopheophytin-containing LH1
38. Comparison of the structural requirements for bacteriochlorophyll binding in the core light-harvesting complexes of Rhodospirillum rubrum and Rhodobacter sphaeroides using reconstitution methodology with bacteriochlorophyll analogs
39. Enzymes of chlorophyll biosynthesis
40. Design, synthesis, and properties of a novel cytochrome b model
41. Combinatorial synthesis of four-helix bundle hemoproteins for tuning of cofactor properties
42. Serine conjugates of chlorophyll and bacteriochlorophyll: Photocytotoxicity in vitro and tissue distribution in mice bearing melanoma tumors
43. The construction of new proteins (III): Artificial folding units by assembly of ampluphilic secondary structures on a template
44. De novo design of redox proteins
45. An improved method for extraction, partial purification, seperation and isolation of Chlorophyll from spinach
46. Chlorophylls: Chromatographic methods for the separation of chlorophylls
47. Preparation and properties of pyrochlorophyll a, methyl pyrochlorophyllide a, pyropheophyin a, and methyl pyropheophorbide a derived from chlorophyll by decarbomethoxylation
48. Selective cleavage of the allyl and allyloxycarbonyl groups through palladium-catalyzed hydrostanniolysis with tributyltin hydride. Application to the selective protection-deprotection of amino acid derivatives and in peptide synthesis
49. Modular synthesis of de novo-designed metalloprotein for light-induced electron transfer
50. Automated allyl cleavage for continuous-flow synthesis of cyclic and branched peptides
51. Resonance Roman spectroscopy of the B820 subunit of the core antenna from Rhodospririllum rubrum G9
52. Recent advances in the biosynthesis and chemistry of the chlorophylls
53. Models of photosynthetic chromophores. Molecular structures of chlorins and bacteriochlorins
54. Stereochemistry and chiroptic properties of Pheophorbides and related compounds
55. Reversible wavelength shifts of chlorophyll induced by a point charge
56. Effects of solvent on the fluorescence properties of bacteriochlorophyll a
57. Y energies of bacteriochlorophyll a and bacteriopheophytin a
58. Metal substituted bacteriochlorophylls 1. Preparation and influence of metal and coordination of spectra
59. Metal substituted bacteriochlorophylls 2. Change in redox and electronic transition energies are dominated by intramolecular electrostatic interactions
60. Chlorophyll aggregates in aqueons solutions
61. Resonance Raman spectroscopy of metal-substituted bacteriochlorophylls: Characterization of Raman bands sensitive to bacteriochlorin conformation
62. Resonance Raman and infrared studies on metal-substituted chlorophyll-A in solution - Correlations between the vibrational frequencies and the core size
63. Vibrational spectroscopy of chlorophylls
64. Metal-sensitive bands in the Raman and infrared spectra of intact and metal-substituted chlorophyll
65. Conformation of bacteriochlorophyll molecules in photosynthetic proteins from purple bacteria
66. Non-bonding molecular factors influencing the stretching wavenumbers of the conjugated carbonyl groups of bacteriochlorophyll a
67. Introduction of a 60 fs deactivation channel in the photosynthetic antenna LH1 by Ni-bacteriopheophytin a
68. Giant circular dichroism of high molecular weight chlorophyllide-apomyoglobin complexes
69. Chlorophyll-amino acid interactions in synthetic models
70. Solution properties of synthetic chlorophyllide- and bacteriochlorophyllide-apomyoglobin complexes
71. Chlorophyllide-substituted hemoglobin tetramers and hybrids: Preparation, characterization, and energy transfer
72. Chemistry of chlorophylls: Modifications