Regulation of vascular endothelial cells and vascular smooth muscle cells by multiple P2Y receptor subtypes

Drug Development Research

Volumn 53, Issue 2-3, 2001, Pages 180-185

  Boarder, Michael R ^a   White, Pamela J ^a   Roberts, Jonathon R ^a,b   Webb, Tania E ^a  

^a DE MONTFORT UNIVERSITY   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Cell cycle; Cyclins; Endothelium; P2 receptors; P27; Proliferation

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CYCLIC AMP; GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROSTACYCLIN; PROTEIN P27; PURINE P2Y RECEPTOR; PURINERGIC RECEPTOR STIMULATING AGENT; RECEPTOR SUBTYPE; URIDINE TRIPHOSPHATE;

ANIMAL CELL; CALCIUM MOBILIZATION; CELL CYCLE; CELL PROLIFERATION; CONFERENCE PAPER; ENDOTHELIUM CELL; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NONHUMAN; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0034843046     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.1186     Document Type: Conference Paper

References (5)

1. 2+, phospliolipase C and mitogen activated protein kinase. Br J Phamacol 122:935-941.
2. Anwar Z, Albert JA, Cubby SE, Boyle JP, Roberts JA, Webb TE, Boarder MR. 1999. Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells. Br J Pharmacol 128:465-471.
3. Boarder MR, Webb TE. 2001. P2Y receptors: structure and function. In: Abbracchio M, Williams M, editors. Handbook of experimental pharmacology, vol. 151, Berlin: Springer-Verlag.
4. 2 purinoceptors on vascular endothelial cells: physiological significance and transduction mechanisms. Trends Pharmacol Sci 11:34-37.
5. 2U-purinoceptor stimulation of prostacyclin release. Br J Pharmacol 116:2463-2568.