Gonadotropin-releasing hormone agonist affects rat ovarian follicle development by interfering with FSH and growth factors on the prevention of apoptosis

Molecular Reproduction and Development

Volumn 60, Issue 2, 2001, Pages 241-247

  Parborell, F ^a   Dain, L ^a   Tesone, M ^a  

^a INST DE BIOL Y MED EXPERIMENTAL   (Argentina)

Author keywords

Apoptosis; Early antral follicles; GnRH; Growth factors; Ovary

Indexed keywords

DIETHYLSTILBESTROL; DNA FRAGMENT; FOLLITROPIN; GONADORELIN AGONIST; GROWTH FACTOR; LEUPRORELIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DNA CLEAVAGE; FEMALE; IN VITRO STUDY; NONHUMAN; OVARY DEVELOPMENT; OVARY FOLLICLE; PREPUBERTY; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BUCLADESINE; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DIETHYLSTILBESTROL; DNA FRAGMENTATION; EPIDERMAL GROWTH FACTOR; ESTROGENS, NON-STEROIDAL; FEMALE; FERTILITY AGENTS, FEMALE; FIBROBLAST GROWTH FACTORS; FOLLICLE STIMULATING HORMONE; FOLLICULAR ATRESIA; GONADOTROPIN-RELEASING HORMONE; INSULIN-LIKE GROWTH FACTOR I; LEUPROLIDE; OVARIAN FOLLICLE; RATS; RATS, SPRAGUE-DAWLEY; SEXUAL MATURATION;

EID: 0034842416     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.1084     Document Type: Article

References (43)

1. Regulation of follicular luteinization by a gonadotropin-releasing hormone agonist: Relationship between steroidogenesis and apotosis
2. Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: Biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells
3. Evidence for a physiological role of gonadotropin-releasing hormone (GnRH) or GnRH-like material in the ovary
4. Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apototic cell death
5. Gonadotropin-releasing hormone analogue binds to luteal cells and inhibits progestrone production
6. Gonadotropin suppression of apotosis in cultured preovulatory follicles mediatory role of endogenous insulin-like growth factor I
7. Hormonal regulation of apoptosis in early antral follicles: Follicle-stimulating hormone as a major survival factor
8. Gonadotropin-releasing hormone: Molecular and cell biology, physiology and clinical applications
9. Extrapituitary actions of gondadotropin-releasing hormone: Stimulation of insulin-like growth factor-binding protein-4 and ateresia
10. Extra pituitary actions of LHRH analogues in tissue of the human female and investigation of the existence and function of LHRH-like peptide
11. Partial characterization of the gonadotropin-releasing hormone (GnRH) gene transcript in the rat ovary
12. Regulation of ovarian follicular development in primates: Facts and hypotheses
13. Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells
14. Development of follicles in the mammalian ovary
15. Morphometric analysis of follicular development in the rat
16. Hormonal regulation of the differentiation of cultured granulosa cells
17. Susceptibility of avian ovarian granulosa cells to apoptosis is dependent upon stage of follicle development and is related to endogenous levels of bcl-xlong gene expression
18. Direct effects of gonadotropin releasing hormone and its antagonist upon ovarian functions stimulated by FSH, prolacting, and LH
19. Inhibition of granulosa cell differentiation by gonadotropin-releasing hormone
20. Intracellular signaling in the gonads
21. Initial and cyclic recruitment of ovarian follicles
22. Preantral ovarian follicles in serum-free culture: Suppression of apoptosis after activation of the cyclic guanosine 3′, 5′-monophosphate pathway and stimulation of growth and differentiation by follicle-stimulating hormone
23. Keratinocyte growth factor promotes the survival, growth, and differentiation of preantral ovarian follicles
24. Gonadotropin-releasing hormone receptor gene expression in human ovary and granulosa-lutein cells
25. Early onset of deoxyribonucleic acid fragmentation during atresia of preovulatory ovarian follicles in rats
26. Homologous and heterologous regulation of gonadotropin-releasing hormone receptor gene expression in preovulatory rat granulosa cells
27. In situ localization of apoptosis in the rat ovary during follicular atresia
28. Mitochondrial peripheral-type benzodiazepine receptor expression. Correlation with gonadotropin-releasing hormone (GnRH) (agonist-induced apoptosis in the corpus luteum
29. Expression and regulation of gonadotropin-releasing hormone (GnRH) receptor messenger ribonucleic acids in human granulosa-luteal cells
30. Ovarian gonadotropin-releasing hormone (GnRH) receptors: Characterization, distribution, and induction by GnRH
31. Inhibition of luteal steroidogenesis by two LHRH antagonists (Nal-Glu and Nal-Arg anatagonists) in the pregnant rat
32. Gonatropin-releasing hormone receptors: Structure and signal transduction pathways
33. Distribution of luteinizing hormone-releasing hormone receptors in the rat ovary
34. Gonadotropin-releasing hormone action on ovarian steroidogenesis and apotosis
35. Cell death and species propagation: Molecular and genetic aspects of apoptosis in the vertebrate female gonad
36. Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles
37. Involvement of apoptosis in ovarian follicular atresia and postovulatory regression
38. Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism
39. 450 aromatase
40. Expression of members of the bcl-2 gene family in the immature rat ovary: Equine chorionic gonadotropin mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong messenger ribonucleic acid levels
41. Life, death and the pursuit of apoptosis
42. Gonadotropin-releasing hormone receptor messenger ribonucleic acid expression in the rat ovary
43. ++ -dependent endonuclease activity in rat granulosa and luteal cells