Cyclooxygenase-2 is overexpressed in serrated adenoma of the colorectum

Diseases of the Colon and Rectum

Volumn 44, Issue 9, 2001, Pages 1319-1323

  Arao, Jun ^a   Sano, Yasushi ^b   Fujii, Takahiro ^b   Kato, Shigeharu ^b   Fu, Kuang I ^b   Yoshino, Takayuki ^b   Ochiai, Atsushi ^b   Fujimori, Takahiro ^a   Yoshida, Shigeaki ^b  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

Author keywords

Cyclooxygenase 2; Hyperplastic polyp; Immunohistochemistry; Serrated adenoma

Indexed keywords

CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR;

ADULT; ARTICLE; CANCER LOCALIZATION; CANCER SIZE; COLORECTAL CANCER; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION;

EID: 0034842355     PISSN: 00123706     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02234791     Document Type: Article

References (27)

1. Nature and significance of hyperplastic polyps of the human colon
2. Pathology of the gastrointestinal tract: Polyps and cancer of the large bowel
3. The adenoma-carcinoma sequence in cancer of the colon
4. Genetic alterations during colorectal-tumor development
5. Mixed hyperplastic adenomatous polyps/serrated adenoma. A distinct form of colorectal neoplasia
6. High frequency of K-ras mutations in human colorectal hyperplastic polyps
7. DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: A mild mutated pathway for colorectal cancer?
8. Ki-67, p53, and Bcl-2 expression of serrated adenomas of the colon
9. Frequent p53 gene mutations in serrated adenomas of the colorectum
10. Aspirin use and reduced risk of fatal colon cancer
11. Treatment of colonic and rectal adenoma with sulindac in familial adenomatous polyposis
12. Aspirin and non-steroidal anti-inflammatory agents and risk for colorectal adenomas
13. Aspirin and the potential role of prostaglandins in colon cancer
14. Chemoprevention of colon carcinogenesis by sulindac, a non-steroidal anti-inflammatory agents
15. Human cyclooxygenase-2 cDNA
16. Purification of the cyclooxygenase that forms prostaglandins
17. Purification of prostaglandin endoperoxidase synthase from bovine vesicular gland microsomes
18. Expression of mRNA for cyclooxygenase-1 and cyclooxygenase-2 in human tissues
19. Cyclooxygenase is an immediate-early gene induced by interleukin-1 in human endothelial cells
20. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
21. Expression of cyclooxygenase-1 and -2 in human colorectal cancer
22. Increased expression of cyclooxygenase-2 to -1 in human colorectal cancers and adenomas, but not in hyperplastic polyps
23. Follow-up patients with hyperplastic polyps of the large bowel
24. Genetic alterations of mixed hyperplastic adenomatous polyps in the colon and rectum
25. Early expression of cyclo-oxygenase-2 during sporadic colorectal carcinogenesis
26. Adenocarcinoma occurring in a hyperplastic (metaplastic) polyp of the colon
27. Differential expression of cyclooxygenase 2 in human colorectal cancer