BJ46a, a snake venom metalloproteinase inhibitor isolation, characterization, cloning and insights into its mechanism of action

European Journal of Biochemistry

Volumn 268, Issue 10, 2001, Pages 3042-3052

  Valente, Richard H ^a   Dragulev, Bojan ^b   Perales, Jonas ^c   Fox, Jay W ^b   Domont, Gilberto B ^a  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b UNIVERSITY OF VIRGINIA   (United States)

^c INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Inhibitor; Metalloproteinase; Reprolysin; Snake venom

Indexed keywords

ACID PROTEIN; AMINO ACID; ATROLYSIN C; BATROXOBIN; BJ 46A; COMPLEMENTARY DNA; DIMER; GLYCOPROTEIN; HABU SERUM FACTOR; JARARHAGIN; MESSENGER RNA; METALLOPROTEINASE; METALLOPROTEINASE INHIBITOR; PROTEINASE INHIBITOR; SIGNAL PEPTIDE; SNAKE VENOM; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLEEDING; CELL TRANSFORMATION; CONTROLLED STUDY; DNA SEQUENCE; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ENZYME INHIBITION; GEL FILTRATION; GENE ISOLATION; GENETIC TRANSCRIPTION; GLYCOSYLATION; LIGHT SCATTERING; MASS SPECTROMETRY; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; RAT; SNAKE; STOICHIOMETRY;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BOTHROPS; CROTALID VENOMS; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENDOPEPTIDASES; ENZYME INHIBITORS; INDICATORS AND REAGENTS; IODOACETAMIDE; ISOELECTRIC FOCUSING; LIGHT; LIVER; METALLOENDOPEPTIDASES; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA, MESSENGER; SCATTERING, RADIATION; SEQUENCE ANALYSIS, DNA; SEQUENCE ANALYSIS, PROTEIN; SNAKE VENOMS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS; VIPER VENOMS;

ANIMALIA; BOTHROPS JARARACA; SERPENTES; TRIMERESURUS FLAVOVIRIDIS;

EID: 0034830642     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02199.x     Document Type: Article

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