The eukaryotic gene transcription machinery

Biological Chemistry

Volumn 382, Issue 8, 2001, Pages 1103-1107

  Kornberg, R D ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Electron microscopy; General transcription factors; Mediator; RNA polymerase II; Two dimensional crystals; X ray crystallography

Indexed keywords

POLYPEPTIDE; RNA POLYMERASE II; TRANSCRIPTION FACTOR;

ARTICLE; EUKARYOTE; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; HELA CELL; HUMAN; HUMAN CELL; MEDIATOR; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; YEAST;

ANIMALS; CRYSTALLOGRAPHY, X-RAY; EUKARYOTIC CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RNA POLYMERASE II; TRANSCRIPTION FACTOR TFIIB; TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS, TFII; TRANSCRIPTION, GENETIC;

EID: 0034826968     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2001.140     Document Type: Article

References (24)

1. Conserved structures of mediator and RNA polymerase II holoenzyme
2. General transcription factors for RNA polymerase II
3. Architecture of RNA polymerase II and implications for the transcription mechanism
4. Structural basis of transcription: RNA polymerase II at 2.8 Å resolution
5. Three-dimensional structure of yeast RNA polymerase II at 16 Å resolution
6. Two-dimensional and epitaxial crystallization of a mutant form of yeast RNA polymerase II
7. Purification and lipid layer crystallization of yeast RNA polymerase II
8. Epitaxial growth of protein crystals on lipid layers
9. A mediator for activation of RNA polymerase II transcription in vitro
10. Yeast RNA polymerase II at 5 Å resolution
11. Structural basis of transcription: An RNA polymerase II elongation complex at 3.3 Å resolution
12. Nucleosome loss activates yeast downstream promoters in vivo
13. A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
14. A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
15. Two-dimensional crystals of proteins on lipid layers
16. Twenty-five years of the nucleosome, fundamental particle of the eukaryote chromosome
17. Two-dimensional crystallography of transcription factor IIB- and IIE-RNA polymerase II complexes: Implications for start site selection and initiation complex formation
18. Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones
19. Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae
20. Multiple factors required for accurate initiation of transcription by purified RNA polymerase II1
21. Mediator of transcriptional regulation
22. II145 functions as a core promoter selectivity factor, not a general coactivator
23. General requirement for RNA polymerase II holoenzymes in vivo
24. TAFs mediate transcriptional activation and promoter selectivity