Large deletion of part of the HMGIC locus accompanying a t(3;12)(q27∼q28;q14∼q15) in a lipoma

Cancer Genetics and Cytogenetics

Volumn 129, Issue 2, 2001, Pages 161-164

  Lemke, Inga ^a   Rogalla, Piere ^a   Bullerdiek, Jörn ^a  

^a UNIVERSITY OF BREMEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT;

ARTICLE; BENIGN TUMOR; CHROMOSOME 12Q; CHROMOSOME 3Q; CHROMOSOME DELETION; CHROMOSOME TRANSLOCATION 12; CHROMOSOME TRANSLOCATION 3; EXON; FLUORESCENCE IN SITU HYBRIDIZATION; FUSION GENE; GENE DELETION; HUMAN; LIPOMA; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOLID TUMOR;

CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 3; CYTOSKELETAL PROTEINS; HIGH MOBILITY GROUP PROTEINS; HMGA2 PROTEIN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; LIPOMA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE DELETION; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0034823932     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00441-1     Document Type: Article

References (13)

1. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains
2. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours
3. Truncated and chimeric HMGI-C genes induce neoplastic transformation of NIH3T3 murine fibroblasts
4. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family
5. An identical HMGIC-LPP fusion transcript is consistently expressed in pulmonary chondroid hamartomas with t(3;12)(q27-q28;q14-q15)
6. Rapid subchromosomal localization of cosmids by nonradioactive in situ hybridization
7. The t(3;12)(q27;q14-15) with underlying HMGIC-LPP fusion is not determining an adipocytic phenotype
8. Cytogenetic profile of 109 lipomas
9. Cytogenetic studies of adipose tissue tumors I. A benign lipoma with reciprocal translocation t(3;12)(q28;q14)
10. A high frequency of tumors with rearrangements of genes of the HMGI(Y) family in a series of 191 pulmonary chondroid hamartomas
11. Frequent and extensive deletion during the 9;22 translocation in CML
12. A submicroscopic interstitial deletion of chromosome 14 frequently occurs adjacent to the t(14;18) translocation breakpoint in human follicular lymphoma