Assessing fertility in women of advanced reproductive age

American Journal of Obstetrics and Gynecology

Volumn 185, Issue 3, 2001, Pages 758-770

  Klein, Jeffrey ^a   Sauer, Mark V ^a  

^a Columbia University ^*  (United States)

Author keywords

Assisted reproduction; Egg donation; Fertility; Ovarian reserve; Reproductive aging

Indexed keywords

ANDROGEN; BASIC FIBROBLAST GROWTH FACTOR; CLOMIFENE CITRATE; EPIDERMAL GROWTH FACTOR; ESTRADIOL; ESTROGEN; FOLLITROPIN; GONADORELIN AGONIST; GONADOTROPIN; GROWTH FACTOR; GROWTH HORMONE; INTERLEUKIN 1BETA; INTERLEUKIN 6; KERATINOCYTE GROWTH FACTOR; LUTEINIZING HORMONE; NITRIC OXIDE; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TUMOR NECROSIS FACTOR ALPHA;

AGING; APOPTOSIS; CELL AGING; FEMALE FERTILITY; GERMINAL VESICLE; HUMAN; MENOPAUSE; NEUROENDOCRINE SYSTEM; NONHUMAN; OOCYTE; OOCYTE DONATION; OVARY; OVULATION; PRIORITY JOURNAL; PROVOCATION TEST; REPRODUCTION; REVIEW; UTERUS;

EID: 0034821637     PISSN: 00029378     EISSN: None     Source Type: Journal    
DOI: 10.1067/mob.2001.114689     Document Type: Article

References (114)

1. Fertility, family planning, and women's health: New data from the 1995 National Survey of Family Growth
2. Impaired fecundity in the United States: 1982-1985
3. Fecundity and infertility in the United States: 1965-88
4. Mom, 54, triplet girls "very well" after births
5. Age and infertility
6. Reproductive span and rate of reproduction among Hutterite women
7. Female fecundity as a function of age: Results of artificial insemination in 2193 nulliparous women with azoospermic husbands
8. The effect of age on female fecundity
9. In-vitro fertilization: Influence of women's age on pregnancy rates
10. Effect of age of the donor and recipient on the development of transferred golden hamster ova
11. Effect of maternal age on viability of ova and uterine support of pregnancy in mice
12. Aging and reproduction in the female mammal with particular reference to the rabbit
13. In vitro fertilization: The degree of endometrial insufficiency varies with the type of ovarian stimulation
14. Evaluating the effect of age on endometrial responsiveness to hormone replacement therapy: A histologic, ultrasonographic, and tissue receptor analysis
15. Normal variation in the length of the luteal phase of the menstrual cycle: Identification of the short luteal phase
16. Poor oocyte quality rather than implantation failure as a cause of age-related decline in female fertility
17. Evidence for an adverse effect of elevated serum estradiol concentrations on embryo implantation
18. Very high serum estradiol levels are not detrimental to clinical outcome of in vitro fertilization
19. Endometrial receptivity for implantation: Another look at the issue of peri-implantation oestrogen
20. Oestrogen and human implantation
21. Hormonal control of endolnetrial receptivity
22. Reversing the natural decline in human fertility: An extended clinical trial of oocyte donation to women of advanced reproductive age
23. Age-related decline in female fertility is not due to diminished capacity of the uterus to sustain embryo implantation
24. A report on 100 cycles of oocyte donation; factors affecting the outcome
25. Endometrial receptivity: The age-related decline in pregnancy rates and the effect of ovarian function
26. Aging of endometrium and oocytes: Observations on conception and abortion rates in an egg donation model
27. The role of maternal age in assisted reproduction
28. Female reproductive aging-ovarian and uterine factors
29. The impact of embryo quality on pregnancy outcome in elderly women undergoing in vitro fertilization-embryo transfer (IVF-ET)
30. Follicular fluid inhibin levels in relation to age in patients in an in vitro fertilization and embryo transfer programme
31. Maternal age effect on early human embryonic development and blastocyst formation
32. Are clinical and biological IVF parameters correlated with chromosomal disorders in early life: A multlcentric study
33. Abnormal chromosome arrangements in human oocytes
34. The meiotic competence of in-vitro matured human oocytes is influenced by donor age: Evidence that folliculogenesis is compromised in the reproductively aged ovary
35. Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities
36. Will preimplantation genetic diagnosis assist patients with a poor prognosis to achieve pregnancy?
37. Age-related decline in fertility: A link to degenerative oocytes?
38. In vitro maturation of human preovulatory oocytes reconstructed by germinal vesicle transfer
39. Birth of an infant after transfer of a nucleate donor oocyte cytoplasm into recipient eggs
40. Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women
41. Culture and selection of viable blastocysts: A feasible proposition for human IVF?
42. Blastocyst culture and transfer: Analysis of results and parameters affecting outcome in two in vitro fertilization programs
43. Decreased amount of ovarian tissue and maternal age affect embryonic development in old rats
44. Smoking and age at menopause in women
45. Constituents of cigarette smoke inhibit human granulosa cell aromatase
46. Cadmium accumulation in follicular fluid of women in in vitro fertilization-embryo transfer is higher in smokers
47. The effects of smoking on ovarian function and fertility during assisted reproduction cycles
48. Accelerated disappearance of ovarian follicles in mid-life: Implications for forecasting menopause
49. Gonadal cell apoptosis
50. Hormonal characteristics of the human menstrual cycle throughout reproductive life
51. Effects of aging on menstrual cycle hormones and endometrial maturation
52. Reproductive aging: Accelerated ovarian follicular development associated with a monotropic follicle-stimulating hormone rise in normal older women
53. Pituitary-ovarian relationships preceding menopause
54. Characterization of reproductive hormonal dynamics in the perimenopause
55. Characteristics of luteinizing hormone secretion in younger versus older premenopausal women
56. Aging of the female reproductive system: A window into brain aging
57. Aging abolishes the estradiol-induced suppression and diurnal rhythm of proopiomelanocortin gene expression in the arcuate nucleus
58. Relationships between insulin-like growth hormone factor-1 and estradiol in reproductive aging
59. Decreased inhibin tone and increased activin A secretion characterize reproductive aging in women
60. The effect of age on the cyclical patterns of plasma LH, FSH, oestradiol, and progesterone in women with regular menstrual cycles
61. Age-related changes in the female reproductive cycle
62. Inhibin concentrations throughout the menstrual cycles of normal, infertile, and older women compared with those during spontaneous conception cycles
63. Relationship between age, percentage body fat, fitness, and 24-hour growth hormone release in healthy young adults: Effects of gender
64. Circulating levels of growth hormone, insulin-like growth factor-I and growth hormone binding protein in normal women of advanced reproductive age
65. Diminished function of the somatotrophic axis in older reproductive-aged women
66. Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age
67. Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: A study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles
68. Growth hormone-binding protein (GH-BP) levels in follicular fluid from human preovulatory follicles: Correlation with serum GH-BP levels
69. Follicular fluid insulin-like growth factor-I and insulin-like growth factor-binding protein-1 and -3 vary as a function of ovarian reserve and ovarian stimulation
70. Effects of aging on the female reproductive system
71. Serum immunoreactive activin A levels in normal subjects and patients with various diseases
72. Immunoradiometric assay for follistatin: Serum immunoreactive follistatin levels in normal adults and pregnant women
73. The potential relevance of growth hormone to female reproductive physiology and pathophysiology
74. Cotreatment with human growth hormone and gonadotropins for induction of ovulation: A controlled clinical trial
75. Co-treatment with growth hormone of sub-optimal responders in IVF-ET
76. Recruitment of fertilizable eggs
77. The value of basal and/or stimulated serum gonadotropin levels in prediction of stimulation response and in vitro fertilization outcome
78. Follicle-stimulating hormone levels on cycle day, 3 are predictive of in vitro fertilization outcome
79. Basal follicle-stimulating hormone level is a better predictor of in vitro fertilization performance than age
80. Significance of basal follicle-stimulating hormone levels in women with one ovary in a program of in vitro fertilization
81. Intercycle variability of day 3 follicle-stimulating hormone levels and its effect on stimulation quality in in vitro fertilization
82. Day 3 estradiol serum concentrations as prognosticators of ovarian stimulation response and pregnancy outcome in patients undergoing in vitro fertilization
83. Basal estradiol and follicle-stimulating hormone predict fecundity in women of advanced reproductive age undergoing ovulation induction therapy
84. Prognostic value of day 3 estradiol on in vitro fertilization outcome
85. Variability of day 3 follicle-stimulating hormone levels in eumenorrheic women
86. Prognostic assessment of female fecundity
87. Prognostic assessment of ovarian reserve
88. Prognostic value of the early serum estradiol response to leuprolide acetate in in vitro fertilization
89. The gonadotropin-releasing hormone agonist stimulation test-a sensitive predictor of performance in the flare-up in vitro fertilization cycle
90. Simultaneous evaluation of basal follicle-stimulating hormone and 17 beta-estradiol response to gonadotropin-releasing hormone analogue stimulation: An improved predictor of ovarian reserve
91. Differential secretion of dimeric inhibin in cultured luteinized granulosa cells as a function of ovarian reserve
92. Inhibin-B: The physiologic basis of the clomiphene citrate challenge test for ovarian reserve screening
93. Dimeric inhibin: A direct marker of ovarian aging
94. Inhibin-B as a test of ovarian reserve for infertile women
95. Measurement of ovarian volume by transvaginal sonography before ovulation induction with human menopausal gonadotrophin for in-vitro fertilization can predict poor response
96. Evaluation of the ovarian reserve in young low responders with normal basal levels of follicle-stimulating hormone using three-dimensional ultrasonography
97. The role of ovarian volume in reproductive medicine
98. A prospective evaluation of clontiphene citrate challenge test screening of the general infertility population
99. Effects of age, treatment, and method of induction on deciduomata in the golden hamster
100. The effect of age upon the connective tissue of the uterus, cervix, and vagina of the rat
101. The cellular response of the uterus of the aged mouse to oestrogen and progesterone
102. Ultrastructure of the uterine luminal epithelium at the time of implantation in aging mice
103. Changes in uterine estrogen receptor morphology in aging female rats
104. Changes in the histomorphology of the uterus of the domestic pig (Sus scrofa domesticus) with advancing age
105. Age changes in density of endometrial stromal cells of the rat
106. Gonadotropin-releasing hormone directly induces apoptotic cell death in the rat ovary: Biochemical and in situ detection of DNA fragmentation in granulosa cells
107. Hormonal regulation of apoptosis in early antral follicles; follicle stimulating hormone as a major survival factor
108. Growth hormone suppression of apoptosis in preovulatory rat follicles and partial neutralization by insulin-like growth factor binding protein
109. Interleukin-1 beta suppresses apoptosis in rat ovarian follicles by increasing nitric oxide production
110. Keratinocyte growth factor promotes survival, growth and differentiation of preantral ovarian follicles
111. Gonadal cell apoptosis: Hormone-regulated cell demise
112. Prediction of individual response to controlled ovarian hyperstimulation by means of clomiphene citrate challenge test
113. Prediction of response to controlled ovarian hyperstimulation: A comparison of basal and clomiphene citrate-stimulated follicle-stimulating hormone levels