Interleukin-4 and tumour necrosis factor-α inhibit transforming growth factor-β production in a human bronchial epithelial cell line: Possible relevance to inflammatory mechanisms in chronic obstructive pulmonary disease

Respirology

Volumn 6, Issue 3, 2001, Pages 205-211

  Hodge, Sandra ^a,b   Hodge, Greg ^c   Holmes, Mark ^a   Flower, Robert ^d   Scicchitano, Raffaele ^a,b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c WOMEN S AND CHILDREN S HOSPITAL   (Australia)

^d ROYAL NORTH SHORE HOSPITAL   (Australia)

Author keywords

Chronic obstructive pulmonary disease; Enzyme linked immunosorbent assay; Flow cytometry; Interleukin 4; Lung epithelial cell; Transforming growth factor ; Tumour necrosis factor

Indexed keywords

INTERLEUKIN 4; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRONCHUS MUCOSA; CELL CULTURE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; PRIORITY JOURNAL; REGULATORY MECHANISM; RESPIRATORY TRACT INFLAMMATION;

BRONCHI; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FLOW CYTOMETRY; HUMANS; INFLAMMATION; INTERLEUKIN-4; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034821210     PISSN: 13237799     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1843.2001.00335.x     Document Type: Article

References (29)

1. Different cytokine patterns in bronchial biopsies in asthma and chronic bronchitis
2. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma
3. Morphological and cellular basis for airflow limitation in smokers
4. IL-4 induces ICAM-1 expression in human bronchial epithelial cells and potentiates TNF-alpha
5. Induction of ICAM-1 expression on human airway, epithelial cells by inflammatory cytokines: Effects on neutrophil-epithelial cell adhesion
6. Phenotyping and cytokine regulation of the BEAS-2B human bronchial epithelial cell: Demonstration of inducible expression of the adhesion molecules VCAM-1 ICAM-1
7. IL-4 directly modulates function of a model human intestinal epithelium
8. Transforming growth factor-beta in normal lung: Preferential location in bronchial epithelial cells
9. Distribution and modulation of the cellular receptor for transforming growth factor-beta
10. Transforming growth factor-β: An important mediator of immunoregulation
11. Interleukin 1, a potential regulator of fibroblast proliferation
12. Immunological functions of the pulmonary epithelium
13. Modulation of fibronectin production of bovine bronchial epithelial cells by transforming growth factor-beta
14. Mutual inhibition by TGF-beta and IL-4 in cultured human bronchial epithelial cells
15. Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecue-1 in vivo. Correlation with CD3+ T cell infiltration
16. In vitro cultivation of human tumors: Establishment of cell lines derived from a series of solid tumors
17. Methyl prednisolone up-regulates monocyte interleukin-10 production in stimulated whole blood
18. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
19. Interleukin-4 alters epithelial cell differentiation and surfactant homeostasis in the postnatal mouse lung
20. The role of transforming growth factor-beta in inflammatory processes
21. Interleukin 1, a potential regulator of fibroblast proliferation
22. Interleukin 1, interleukin 6, tumor necrosis factor, and transforming growth factor beta increase cell resistance to tumor necrosis factor cytotoxicity by growth arrest in the G1 phase of the cell cycle
23. Transforming growth factor-beta stimulates expression of fibronectin and collagen and their incorporation into the extracellular matrix
24. Regulation of vascular cell adhesion molecule-1 expression by IL-4 and TNF-α in cultured endothelial cells
25. Altered compartmentalization of transforming growth factor-β in asthmatic airways
26. Transforming growth factor-β expression in mucosal biopsies in asthma and chronic bronchitis
27. Transforming growth factor beta 1 gene expression in human airways
28. Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics
29. Interleukin 4 is localised to and released by human mast cells