Altered compartimentalization of transforming growth factor-β in asthmatic airways

Clinical and Experimental Allergy

Volumn 27, Issue 4, 1997, Pages 389-395

  Magnan, A ^a,c   Retornaz, F ^a   Tsicopoulos, A ^b   Brisse, J ^c   Van Pee, D ^a   Gosset, P ^b   Chamlian, A ^c   Tonnel, A B ^c   Vervloet, D ^a  

^a Ste Marguerite Hospital   (France)

^b INSTITUT PASTEUR DE LILLE   (France)

^c HÔPITAL SAINTE MARGUERITE   (France)

Author keywords

Asthma; Bronchial epithelial cells; Cytokines; Inflammation; Lung; Mucosal immunity; TGF

Indexed keywords

CYTOKINE; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ARTICLE; ASTHMA; BASEMENT MEMBRANE; BRONCHUS BIOPSY; BRONCHUS MUCOSA; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG FIBROSIS; PRIORITY JOURNAL; AGED; BRONCHUS; CASE CONTROL STUDY; EPITHELIUM; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MUCOSAL IMMUNITY; PATHOLOGY; TISSUE DISTRIBUTION;

ADULT; AGED; ASTHMA; BASEMENT MEMBRANE; BRONCHI; CASE-CONTROL STUDIES; EPITHELIUM; HUMANS; IMMUNITY, MUCOSAL; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; TISSUE DISTRIBUTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0030609953     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.1997.tb00723.x     Document Type: Article

References (30)

1. Hamid Q, Azzawi M, Ying S et al. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J Clin Invest 1991; 87:1541-6.
2. Bousquet J, Chanez P, Lacoste JY. Eosinophilic inflammation in asthma. New Engl J Med 1990; 323:1033-9.
3. Marini M, Vittori E, Hollemborg J, Mattoli S. Expression of the potent inflammatory cytokines, granulocyte-macrophage colony stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma. J Allergy Clin Immunol 1992; 89:1001-9.
4. Wang JH, Trigg CJ, Devalia JL, Jordan S, Davies RJ. Effect of inhaled beclometasone dipropionate on expression of proinflammatory cytokines and activated eosinophils in the bronchial epithelium of patients with mild asthma. J Allergy Clin Immunol 1994; 94:1025-34.
5. Sousa R, Poston RN, Lane SJ, Nakhosteen JA, Lee TH. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am Rev Respir Dis 1993; 147:1557-61.
6. Sacco O, Romberger D. Rizzino A et al. Spontaneous production of transforming growth factor-β2 by primary cultures of bronchial epithelial cells. J Clin Invest 1992; 90:1379-85.
7. Roberts AB, Sporn M, Assoian RK et al. Transforming growth factor type β: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA 1986; 83:4167-71.
8. Magnan A, Frachon I, Rain B et al. Transforming growth factor-beta in normal human lung: preferential location in bronchial epithelial cells. Thorax 1994; 49:789-92.
9. Aas K. Heterogeneity of bronchial asthma. Allergy 1981; 36:3-10.
10. Magnan A, Mege JL, Escallier JC et al. Balance between alveolar macrophage IL-6 and TGF-β in lung transplant recipients. Am J Respir Crit Care Med 1996; 153:1431-6.
11. Shi SR, Key ME, Kalra K. Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement methods for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 1991; 39:741-8.
12. Khalil N, O'Connor RN, Unruh HW et al. Increased production and immunohistochemical location of transforming growth factor-β in idiopathic pulmonary fibrosis. Am J Respir Cell Mol Biol 1991; 5:155-62.
13. Broekelmann TJ, Limper AH, Colby TV, McDonald JA. Transforming growth factor-β is present at sites of extracellular matrix gene expression in human pulmonary fibrosis. Proc Natl Acad Sci USA 1991; 88:6642-6.
14. Aubert JD, Dalal BI, Bai TR et al. Transforming growth factor-β1 gene expression in human airways. Thorax 1994; 49:225-32.
15. AyanlarBatuman O, Ferrero AP, Diaz A, Jimenez SA. Regulation of transforming growth factor-β1 gene expression by glucocorticoids in normal human T lymphocytes. J Clin Invest 88: 1574-80.
16. Lundqvist C, Baranov V, Teglund S, Hammarström S, Hammarström ML. Cytokine profile and ultrastructure of intraepithelial γδ T cells in chronically inflamed gingiva suggest a cytotoxic effector function. J Immunol 1994; 153:2302-12.
17. Derynck R, Jarrett A, Chen EY et al. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature 1985; 316:701-5.
18. Tsunawaki S, Sporn M, Ding A, Nathan C. Deactivation of macrophages by transforming growth factor-β. Nature 1988; 334:260-2.
19. Fontana A, Frei K, Bodmer S et al. Transforming growth factor-β inhibits the generation of cytotoxic T cells in virus-infected mice. J Immunol 1989; 143:3230-4.
20. Fargeas C, Wu CY, Nakajima T, Cox D, Nutman T, Delespesse G. Differential effects of transforming growth factor-β on the synthesis of Th1- and Th2-like lymphokines by human T lymphocytes. Eur J Immunol 1992; 22:2173-6.
21. Shull MM, Ormsby L, Kier AB et al. Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease. Nature 1992; 359:693-9.
22. Kulkarni AB, Huh CG, Becker D et al. Transforming growth factor-β1 null mutation in mice causes excessive inflammatory response and early death. Proc Natl Acad Sci USA 1993; 90:770-4.
23. Resnick MB, Weller PF. Mechanisms of eosinophil recruitment. Am J Respir Cell Mol Biol 1993; 8:349-55.
24. Chen BDM, Mueller M, Chou T. Role of granulocyte/macrophage colony stimulating factor in the regulation of murine alveolar macrophage proliferation and differentiation. J Immunol 1988; 141:139-44.
25. Allerga L, Fabbri LM, Picotti G, Mattoli S. Bronchial epithelium and asthma. Eur Respir J 1989; 2(Suppl. 6):460s-8s.
26. Sporn MB, Roberts AB. Transforming growth factor-β: recent progress and new challenges. J Cell Biol 1992; 119:1017-21.
27. Ohno I, Lea RG, Flanders KC et al. Eosinophils in chronically inflamed upper airway tissues express transforming growth factor β1 gene (TGF-β1). J Clin Invest 1992; 89:1662-9.
28. Elovic A, Wong DTW, Weller PF, Matossian K, Galli SJ. Expression of transforming growth factors-α and β1 messenger RNA and product by eosinophils in nasal polyps. J Allergy Clin Immunol 1994; 93:864-9.
29. Border WA, Noble NA. Transforming growth factor-β in tissue fibrosis. N Engl J Med 1994; 331:1286-92.
30. Roche WR, Beasley R, Williams JH, Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989; i:520-3.