Geographic variation in patient and hospital characteristics, management, and clinical outcomes in ST-elevation myocardial infarction treated with fibrinolysis: Results from InTIME-II

European Heart Journal

Volumn 22, Issue 18, 2001, Pages 1702-1715

  Giugliano, Robert P ^a,e   Llevadot, J ^a   Wilcox, R G ^b   Gurfinkel, E P ^c   McCabe, C H ^a   Charlesworth, A ^d   Thompson, S L ^d   Antman, E M ^a   Braunwald, E ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

^c HOSPITAL UNIVERSITARIO FUNDACIÓN FAVALORO   (Argentina)

^d Nottingham Clinical Research Group   (United Kingdom)

^e TIMI Study Office   (United States)

Author keywords

Fibrinolysis; Geographic variation; Management; Myocardial infarction; Outcomes

Indexed keywords

ACETYLSALICYLIC ACID; ALTEPLASE; ANTIARRHYTHMIC AGENT; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOLYTIC AGENT; HEPARIN; LANOTEPLASE;

ADULT; AGED; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CORONARY ARTERY BYPASS SURGERY; CORONARY ARTERY DISEASE; FEMALE; FIBRINOLYTIC THERAPY; GEOGRAPHIC DISTRIBUTION; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HOSPITAL UTILIZATION; HUMAN; HYPERLIPIDEMIA; MAJOR CLINICAL STUDY; MALE; MORTALITY; OUTCOMES RESEARCH; PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY; PRIORITY JOURNAL; STROKE; TREATMENT OUTCOME;

ADULT; AGED; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANTILIPEMIC AGENTS; CARDIAC SURGICAL PROCEDURES; DATA COLLECTION; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY; ENDPOINT DETERMINATION; EUROPE; EUROPE, EASTERN; FEMALE; FIBRINOLYTIC AGENTS; FOLLOW-UP STUDIES; GEOGRAPHY; HOSPITALS; HUMANS; LATIN AMERICA; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NORTH AMERICA; PATIENTS; RECEPTORS, ANGIOTENSIN; TREATMENT OUTCOME;

EID: 0034820167     PISSN: 0195668X     EISSN: None     Source Type: Journal    
DOI: 10.1053/euhj.2001.2583     Document Type: Article

References (31)

1. Shattuck lecture - Cardiovascular medicine at the turn of the millennium: Triumphs, concerns, and opportunities
2. A comparison of management patterns after acute myocardial infarction in Canada and the United States
3. Comparative case fatality analysis of the International Tissue Plasminogen Activator/Streptokinase Mortality Trial: Variation by country beyond predictive profile
4. Variations in patient management and outcomes for acute myocardial infarction in the United States and other countries. Results from the GUSTO trial. Global Utilization of Streptokinase and Tissue Plasminogen activator for occluded coronary arteries
5. Regional variation across the United States in the management of acute myocardial infarction. GUSTO-1 Investigators. Global Utilization of Streptokinase and Tissue Plasminogen activator for occluded coronary arteries
6. The ENACT study: A pan-European survey of acute coronary syndromes
7. Clinical outcomes, risk stratification and practice patterns of unstable angina and myocardial infarction without ST elevation: Prospective Registry of Acute Ischaemic Syndromes in the UK (PRAIS-UK)
8. Inter-regional differences and outcome in unstable angina. Analysis of the International ESSENCE trial
9. Acute myocardial infarction: Pre-hospital in-hospital management. The Task Force on the Management of Acute Myocardial Infarction of the European Society of Cardiology
10. ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction)
11. Current treatment and future prospects for the management of acute coronary syndromes
12. Intravenous NPA for the Treatment of Infarcting Myocardium Early: InTIME-II, a double-blind comparison of single-bolus lanoteplase vs accelerated alteplase for the treatment of patients with acute myocardial infarction
13. Variation in the use of cardiac procedures after acute myocardial infarction
14. Use of cardiac procedures and outcomes in elderly patients with myocardial infarction in the United States and Canada
15. Patterns of practice for acute myocardial infarction in a population from ten countries
16. Use of coronary angiography and revascularization procedures following acute myocardial infarction. A European perspective
17. For the InTIME (Intravenous nPA for Treatment of INfarcting Myocardium Early) II Investigators. Availability of on-site catheterization and clinical outcomes in patients receiving fibrinolysis for ST-elevation myocardial infarction
18. TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for Treatment of Infarcting Myocardium Early II Trial Substudy
19. Variations between countries in invasive cardiac procedures and outcomes in patients with suspected unstable angina or myocardial infarction without initial ST elevation
20. Geographic variability in outcomes within an international trial of glycoprotein IIb/IIIa inhibition in patients with acute coronary syndromes. Results from PURSUIT
21. Inter-regional differences in acute coronary syndrome trials
22. Immediate versus deferred beta-blockade following thrombolytic therapy in patients with acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI) II-B Study
23. Timolol-induced reduction in mortality and reinfarction in patients surviving acute myocardial infarction
24. Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial
25. Effect of beta-blockade on mortality among high-risk and low-risk patients after myocardial infarction
26. 1999 Update: ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Acute Myocardial Infarction)
27. A comparison of U.S. and Canadian cardiac catheterization practices in detecting severe coronary artery disease after myocardial infarction: Efficiency, yield and long-term implications
28. Ten-year follow-up of survival and myocardial infarction in the randomized Coronary Artery Surgery Study
29. Effect of coronary artery bypass graft surgery on survival: Overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration
30. Use of medical resources and quality of life after acute myocardial infarction in Canada and the United States
31. Quality of life after acute myocardial infarction in patients treated at sites with and without catheterization laboratories