Oral bioavailability of dihydroartemisinin in vietnamese volunteers and in patients with falciparum malaria

British Journal of Clinical Pharmacology

Volumn 51, Issue 6, 2001, Pages 541-546

  Binh, Tran Quang ^a   Ilett, Kenneth F ^b   Batty, Kevin T ^c   Davis, Timothy M E ^b   Hung, Nguyen Canh ^d   Powell, Shane M ^a   Thu, Le Thi Anh ^a   Van Thien, Huynh ^b   Phuöng, Hoang Lan ^b   Phuong, Vu Duong Bich ^c  

^a CHO RAY HOSPITAL   (Viet Nam)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c Medical Research   (Australia)

^d Bao Loc Hospital   (Viet Nam)

Author keywords

Artesunate; Bioavailability; Dihydroartemisinin; Falciparum malaria; Pharmacodynamics; Pharmacokinetics

Indexed keywords

ARTESUNATE; DIHYDROARTEMISININ; MEFLOQUINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CALCULATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; EXPOSURE; FEVER; FIRST PASS EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALARIA FALCIPARUM; MEASUREMENT; PARASITE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TIME; VIET NAM; VOLUNTEER;

ADMINISTRATION, ORAL; ADULT; ANTIMALARIALS; ARTEMISININS; BIOLOGICAL AVAILABILITY; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; MALARIA, FALCIPARUM; METABOLIC CLEARANCE RATE; SESQUITERPENES; TIME FACTORS; VIETNAM;

EID: 0034818671     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2001.01395.x     Document Type: Article

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