Prolonged leaching time of peptide antibiotics from acrylic bone cement

Clinical Orthopaedics and Related Research

Volumn 363, Issue , 1999, Pages 232-239

  Yaniv, M ^a,b   Dabbi, D ^a,b   Amir, H ^a,b   Cohen, S ^a   Mozes, M ^c   Tsuberi, H ^d   Frietkin, M ^d   Dekel, S ^b   Ofek, I ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^c KAPLAN HOSPITAL   (Israel)

^d WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACRYLIC CEMENT; ERYTHROMYCIN; GENTAMICIN; NOVOBIOCIN; POLYMYXIN B NONAPEPTIDE; POLYPEPTIDE ANTIBIOTIC AGENT; VANCOMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; BONE INFECTION; CONTROLLED STUDY; DRUG PENETRATION; ESCHERICHIA COLI; KLEBSIELLA PNEUMONIAE; MALE; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RABBIT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; TIBIA;

EID: 0033038990     PISSN: 0009921X     EISSN: 15281132     Source Type: Journal    
DOI: 10.1097/00003086-199906000-00030     Document Type: Article

References (20)

1. Adams K, Couch L, Cierny G, et al: In vitro and in vivo evaluation of antibiotic diffusion from antibiotic impregnated polymethyl methacrylate beads. Clin Orthop 278:244-252, 1992.
2. Baystorn R, Milner RDG: The sustained release of antimicrobial drugs from bone cement. An appraisal of laboratory investigations and their significance. J Bone Joint Surg 64B:460-464, 1982.
3. Brien WW, Salvati EA, Klein R, Brause B, Stern S: Antibiotic impregnated bone cement in total hip arthroplasty. An in vivo comparison of the elution properties of tobramycin and vancomycin. Clin Orthop 296:242-248, 1993.
4. Brown WJ: Microbiology of the infected total joint arthroplasty. Semin Arthroplasty 5:107-113, 1994.
5. Carlsson AK, Lidgren L, Lindberg L: Prophylactic antibiotics against early and late deep infections after total hip replacements. Acta Orthop Scand 48:405-410, 1977.
6. Charnley J: Postoperative infection after total hip replacement with special reference to air contamination in operating room. Clin Orthop 87:167-187, 1972.
7. Davies JP, Harris WH: Effect of hand mixing tobramycin on the fatigue strength of Simplex P. J Biomed Mater Res 25:1409-1414, 1991.
8. Duncan CP, Beauchamp C: A temporary antibiotic-loaded joint replacement system of an infections involving the hip. Orthop Clin North Am 24:751-759, 1993.
9. Elson RA, Jephcott AE, McGechie DB, Verettas D: Antibiotic-loaded acrylic cement. J Bone Joint Surg 59B:200-205, 1977.
10. Ericson C, Lidgren L, Lindberg L: Cloxacillin in the prophylaxis of postoperative infections of the hip. J Bone Joint Surg 55A:808-813, 1973.
11. Fitzgerald RH. Problems associated with the infected total hip arthroplasty. Clin Rheum Dis 12:537-554, 1986.
12. Garvin KL, Evans BG, Salvati EA, et al: Palacos gentamicin for the treatment of deep periprosthetic hip infections. Clin Orthop 298:97-105, 1994.
13. Henry SL, Seligson D, Magno P, Popham GJ: Antibiotic-Impregnated Beads. Complications of Total Hip Replacements. In Mueller ME (ed). The Hip. Proceedings of the Second Open Meeting of The Hip Society. St Louis, CV Mosby 319-321, 1974.
14. Hill C, Flamant R, Mazas F: Prophylactic Cefazolin versus placebo in total hip replacement. Report of a multicentre double-blind randomized trial. Lancet 1:795-796, 1981.
15. Hope PG, Kristinsson KG, Norman P, Elson RA: Deep infection of cemented total hip arthroplasties caused by coagulase negative staphylococci. J Bone Joint Surg 71B:851-855, 1989.
16. Kuechle DK, Landon GC, Musher DM, Noble PC: Elution of Vancomycin, daptomycin, and amikacin from acrylic bone cement. Clin Orthop 264:302-308, 1991.
17. Lawson KJ, Marks KE, Brems J, Rehm S: Vancomycin vs. tobramycin elution from polymethyl-methacrylate: An in vitro study. Orthopedics 13:521-524, 1990.
18. Ofek I, Cohen S, Rahmani R, et al: Antibacterial synergism of polymyxin B nonapeptide and hydrophobic antibiotics in experimental gram negative infections in mice. Antimicrob Agents Chemother 38:374-377, 1994.
19. Seyral P, Zannier A, Argenson JN, Raoult D: The release in vitro of Vancomycin and tobramycin from acrylic bone cement. J Antimicrob Chemother 33:337-339, 1994.
20. Vaara M: Agents that increase the permeability of the outer membrane. Microbiol Rev 56:395-411, 1992.