Inhibition of oligo(glutamine) precipitation by glutamine-containing peptides

Biochemical and Biophysical Research Communications

Volumn 283, Issue 2, 2001, Pages 351-355

  Chu, B C F ^a   Orgel, L E ^a  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

Alternating glutamine containing peptides; Inhibition of precipitation; Poly(glutamine)

Indexed keywords

ARGINYLGLUTAMYLARGINYLGLUTAMYLARGINYLGLUTAMYLARGINYLGLUTAMYLARGINYLGLUTAMYL ARGINYLGLUTAMYLARGINYLGLUTAMYLARGINYLGLUTAMYL; CARBONYLDIIMIDAZOLE; GLUTAMINYLGLUTAMYLGLUTAMINYLGLUTAMYLGLUTAMINYLGLUTAMYLGLUTAMINYLGLUTAMYL; IMIDAZOLE DERIVATIVE; OCTAPEPTIDE; OLIGO(GLUTAMINE); OLIGOPEPTIDE; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; HYDROGEN BOND; NONHUMAN; PEPTIDE SYNTHESIS; PRECIPITATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STRUCTURE;

EID: 0034817377     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.4778     Document Type: Article

References (8)

1. Glutamine repeats and neurodegeneration
2. Gain of glutamines, gain of function?
3. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias
4. Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
5. Glutamine repeats as polar zippers: Their possible role in inherited neurodegenerative diseases
6. N,N′-Carbonyldiimidazole-induced peptide formation in aqueous solution
7. Polar amino acid-rich sequences bind to polyglutamine tracts
8. Inhibition of polyglutamine protein aggregation and cell death by novel peptides identified by phage display screening