A comparison of the stage-specific efficacy of chloroquine, artemether and dioncophylline B against the rodent malaria parasite Plasmodium chabaudi chabaudi in vivo

Parasitology Research

Volumn 87, Issue 10, 2001, Pages 795-803

  Chimanuka, B ^a   Francois G ^b,d   Timperman, G ^b   Heyden, Vander Y ^a   Holenz, J ^c   Plaizier Vercammen, J ^a   Bringmann, G ^c  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; CHLOROQUINE; DIONCOPHYLLINE B; ISOQUINOLINE ALKALOID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; FEMALE; MALARIA; MOUSE; NONHUMAN; PARASITE CONTROL; PARASITE DEVELOPMENT; PARASITEMIA; PLASMODIUM CHABAUDI; PRIORITY JOURNAL; SCHIZONT; TREATMENT OUTCOME; TROPHOZOITE;

ANIMALS; ANTIMALARIALS; ARTEMISININS; CHLOROQUINE; FEMALE; ISOQUINOLINES; LIFE CYCLE STAGES; MALARIA; MICE; PARASITEMIA; PLASMODIUM CHABAUDI; SESQUITERPENES;

ANIMALIA; PLASMODIUM CHABAUDI; PLASMODIUM CHABAUDI CHABAUDI; PROTOZOA; RODENTIA;

EID: 0034816441     PISSN: 09320113     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004360000358     Document Type: Article

References (40)

1. Effects of chloroquine on the morphology of the erythrocytic stages of Plasmodium gallinaceum
2. Pour des nouveaux antipaludéens: Les voies de la recherche fondamentale
3. Reaction of antimalarial endoperoxides with specific parasite proteins
4. Novel antiparasitic biaryl alkaloids from West African Dioncophyllaceae plants
5. Dioncophylline B, a naphthylisoquinoline alkaloid with a new coupling type from Triphyophyllum peltatum
6. Clinical trial of artesunate and artemether on multidrug resistant, falciparum malaria in Thailand. A preliminary report
7. Plasmodium vinckei petteri: Identification of the stages sensitive to arteether
8. Chronotherapy of malaria: Identification of drug-sensitive stage of parasite and timing of drug delivery for improved therapy
9. Chronobiology of Plasmodium chabaudi chabaudi: Analysis of hourly recorded total and differential parasitaemia during a schizogonic cycle
10. Influence of the host photoperiodicity on the schizogonic cycle and the synchronism of the rodent malaria parasite Plasmodium chabaudi chabaudi
11. Complex formation between chloroquine and ferrihemic acid in vitro and its effect on the antimalarial action of chloroquine
12. Host heme catabolism in drug sensitive and drug resistant malaria
13. Economic prospects for a new antimalarial drug
14. Activity of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and A. barteri against Plasmodium falciparum in vitro
15. Differential sensitivity of erythrocytic stages of the rodent malaria parasite Plasmodium chabaudi chabaudi to dioncophylline B, a highly active naphthylisoquinoline alkaloid
16. Antimalarial activity of mefloquine and qinghaosu
17. Comparison of artemether and quinine in the treatment of severe falciparum malaria in south-east Thailand
18. Science, medicine, and the future malaria
19. Description de Plasmodium chabaudi n. sp., parasite de rongeurs africains
20. Chronotherapy of malaria: Improved efficacy of timed chloroquine treatment of patients with Plasmodium falciparum infections
21. Morphological effects of chloroquine on Plasmodium berghei in mice
22. The mode of action of antimalarial endoperoxides
23. Artemisinin (qinghaosu): The role of intracellular hemin in its mechanism of antimalarial action
24. Iron dependent free radical generation from the antimalarial artemisinin (qinghaosu)
25. Artemisinin and the antimalarial endoperoxides: From herbal remedy to targeted chemotherapy
26. An open randomised trial of artemether versus quinine in the treatment of cerebral malaria in African children
27. Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite
28. A controlled clinical trial of artemether (qinghaosu derivative) versus quinine in complicated and severe falciparum malaria
29. Parenteral therapy of moderately severe malaria: Comparison of intramuscular artemether and intramuscular sulfadoxine-pyrimethamine
30. In vitro stage-specific sensitivity of Plasmodium falciparum to quinine and artemisinin drugs
31. A common mechanism for blockade of heme polymerization by antimalarial quinolines
32. Malaria: Drug use and the immune response
33. The combined use of artemether, sulphadoxine and pyrimethamine in the treatment of uncomplicated falciparum malaria
34. Mode of action of chloroquine on Plasmodium berghei and Plasmodium cynomolgi
35. The chemotherapy of rodent malaria XX. Autophagic vacuole formation in Plasmodium berghei in vitro
36. Pharmacology and pharmacokinetics of new antimalarials
37. Comparison of artemether and chloroquine for severe malaria in Gambian children
38. Plasmodium lophurae: Composition and properties of hemozoin, the malarial pigment
39. Stage-dependent effect of chloroquine on Plasmodium falciparum in vitro
40. The rate of ferriprotoporphyrin IX in malaria infected erythrocytes in conjugation with the mode of action of antimalarial drugs