Cyclooxygenase inhibitors are potent sensitizers of prostate tumours to hyperthermia and radiation

International Journal of Hyperthermia

Volumn 17, Issue 5, 2001, Pages 401-414

  Asea, A ^a   Mallick, R ^a   Lechpammer, S ^a   Ara, G ^a   Teicher, B A ^a   Fiorentino, S ^a   Stevenson, M A ^a   Calderwood, S K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Cyclooxygenase; Hyperthermia; Non steroidal anti inflammatory drugs; Prostate cancer; Radiation; Thermotolerance

Indexed keywords

IBUPROFEN; LEUKOTRIENE B4; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; SULINDAC;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER RADIOTHERAPY; CLINICAL PROTOCOL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG POTENTIATION; DRUG RESPONSE; DRUG USE; HEAT TOLERANCE; HYPERTHERMIC THERAPY; MALE; MOUSE; NONHUMAN; PROSTAGLANDIN BLOOD LEVEL; PROSTAGLANDIN RELEASE; PROSTAGLANDIN SYNTHESIS INHIBITION; PROSTATE TUMOR; RADIOSENSITIZATION; SENSITIZATION; SERUM; TUMOR GROWTH;

ANIMALS; COMBINED MODALITY THERAPY; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; HUMANS; HYPERTHERMIA, INDUCED; IBUPROFEN; LEUKOTRIENE B4; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROSTATIC NEOPLASMS; RADIATION-SENSITIZING AGENTS; SULINDAC;

EID: 0034815387     PISSN: 02656736     EISSN: None     Source Type: Journal    
DOI: 10.1080/02656730110058600     Document Type: Article

References (32)

1. Reduced incidence of colorectal adenoma among long-term users of nonsteroidal antiinflammatory drugs: A pooled analysis of published studies and a new population-based study
2. Non-steroidal antiinflammatory drugs and bladder cancer prevention
3. Pain management in patients with advanced prostate cancer
4. Sulindac sulfone inhibits K-ras-dependent cyclooxygenase-2 expression in human colon cancer cells
5. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis
6. Nonsteroidal antiinflammatory drugs inhibit the proliferation of colon adenocarcinoma cells: Effects on cell cycle and apoptosis
7. Improvement in therapeutic ratio of radiotherapy for a murine sarcoma by indomethacin plus misonidazole
8. Combined antitumor effect of radiation and ibuprofen in human prostate carcinoma cells
9. Non-steroidal anti-inflammatory drugs
10. Nonsteroidal antiinflammatory drugs: Differences and similarities
11. Non-steroidal anti-inflammatory drugs inhibit the expression of cytokines and induce HSP70 in human monocytes
12. Salicyclic acid and aspirin inhibit the activity of RSK2 kinase and repress RSK2-dependent transcription of CREB and NF-κB responsive genes
13. Heat shock stimulates the release of arachidonic acid and the synthesis of prostaglandins and leukotriene B4 in mammalian cells
14. Signalling through NK1.1 triggers NK cells to die but induces NKT cells to produce interleukin-4
15. Inhibition of heat shock gene expression does not block the development of thermotolerance
16. Induction of thermotolerance by prostaglandin A in human cells
17. Modulation of prostaglandin A1-induced thermotolerance by quercetin in human leukemic cells: Role of heat shock protein 70
18. Biological and clinical aspects of hyperthermia in cancer therapy
19. The importance of thermotolerance for the clinical treatment with hyperthermia
20. Modulation of prostaglandin A1-induced thermotolerance by quercetin in human leukemic cells: Role of heat shock protein 70
21. Natural thermal resistance of human tumor cells and the role of prostaglandin
22. Reciprocal effects of pro-inflammatory stimuli and antiinflammatory drugs on the activity of heat shock factor-1 in human monocytes
23. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
24. Inhibition of NF-kappa B by sodium salicylate and aspirin
25. Effect of sodium salicylate on the human heat shock response
26. Sodium salicylate and yeast heat shock gene transcription
27. Sodium salicylate decreases intracellular ATP, induces both heat shock factor binding and chromosomal puffing, but does not induce hsp 70 gene transcription in Drosophila
28. Transduction of the stress signal and mechanisms of transcriptional regulation of heat shock/stress protein gene expression in higher eukaryotes
29. NF-kappa B: Ten years after
30. Inducers of the heat shock response stimulate phospholipase C and phospholipase A2 activity in mammalian cells
31. Regulation of constitutive cyclo-oxygenase-2 expression in colon carcinoma cells