Polyamines and colon cancer

European Journal of Gastroenterology and Hepatology

Volumn 13, Issue 9, 2001, Pages 1033-1039

  Wallace, H M ^a   Caslake, R ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Cancer chemotherapy; Ornithine decarboxylase; Putrescine; Spermidine; Spermine

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT; ORNITHINE DECARBOXYLASE; PUTRESCINE; SPERMIDINE; SPERMINE;

CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER SURVIVAL; CELL DIFFERENTIATION; CELL GROWTH; COLON CANCER; DIETARY FIBER; HUMAN; HUMAN CELL; MONITORING; POLYAMINE METABOLISM; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SURVIVAL RATE;

COLORECTAL NEOPLASMS; DIET; FEMALE; HUMANS; MALE; POLYAMINES; PROGNOSIS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 0034812923     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042737-200109000-00006     Document Type: Review

References (54)

1. Estimates of the worldwide incidence of eighteen major cancers in 1985
2. Science, medicine, and the future: Colorectal cancer
3. Natural history of colorectal cancer
4. Correlating nutrition to recent cancer mortality statistics
5. The multistep nature of cancer
6. Lessons from hereditary colorectal cancer
7. Colon cancer prevention: Intervening in a multistage process
8. Colorectal cancer: Molecules and populations
9. Polyamines in rapid growth and cancer
10. Elevation of monoacetylated polyamines in human breast cancers
11. Polyamines in breast cancer
12. Polyamines in colorectal cancer
13. Polyamines and human health
14. Polyamines, chromatin structure and transcription
15. Uptake and excretion of polyamines from baby hamster kidney cells (BHK-21/C13): The effect of serum on confluent cell cultures
16. Effect of growth conditions on the activity of ornithine decarboxylase in cultured hepatoma cells
17. Rapid and regulated degradation of ornithine decarboxylase
18. Regulation of polyamine acetylation and efflux in human cancer cells
19. Implications and concepts of polyamine - Nucleic acid interactions
20. Molecular genetics of polyamine synthesis in eukaryofic cells
21. Specificity and binding in polyamine/nucleic acid interactions
22. Influence of polyamines on membrane functions
23. The natural polyamine spermine functions directly as a free radical scavenger
24. Urinary polyamines in cancer patients
25. Altered polyamine excretion in Duchenne muscular dystrophy
26. Urinary polyamine levels in patients with psoriasis
27. Pattern and concentration of free and acetylated polyamines in urine of cirrhotic patients
28. Polyamines and the clinical evaluation of patients with cancer
29. Serum polyamine alterations in surgical patients with colorectal carcinoma
30. Ornithine decarboxylase activity in rat and human colon
31. High ornithine decarboxylase activity and polyamine levels in human colorectal neoplasia
32. Polyamine oxidase activity and polyamine levels in human colorectal cancer and in normal surrounding mucosa
33. Alterations in polyamine catabolic enzymes in human breast cancer tissue
34. Polyamine metabolism and its importance in neoplastic growth and as a target for chemotherapy
35. Polyamines as targets for therapeutic intervention
36. Intracellular putrescine and spermidine deprivation induces increased uptake of the natural polyamines and methylglyoxal bis(guanylhydrazone)
37. Polyamine deprivation enhances antitumoural efficacy of chemotherapy
38. Suppression of preneoplastic changes in the intestine of rats fed low levels of polyamines
39. 8-spermidine derivatives in cultured L1210 leukaemic cells
40. Synthetic polyamine analogues as antineoplastics
41. 1-acetyltransferase (SSAT) and as potential antitumour agents
42. New S-adenosylmethionine decarboxylase inhibitors with potent antitumour activity
43. Ornithine decarboxylase as a biological marker in familial polyposis coli
44. Ornithine decarboxylase and polyamines in familial polyposis coli
45. Chemoprevention of cancer
46. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
47. Hypothesis: Non-steroidal anti-inflammatory drugs reduce the incidence of large bowel cancer
48. Differential growth inhibition by the aspirin metabolite salicylate in human colorectal tumour cell lines: Enhanced apoptosis in carcinoma and in vitro transformed adenoma relative to adenoma cell lines
49. Cytotoxicity of non-steroidal anti-inflammatory drugs in human cancer cells
50. Effects of non-steroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin independent pathway
51. Sulindac sulphone inhibits azoxymethane induced colon carcinogenesis in rats without reducing prostaglandin levels
52. Chemopreventative drug development: Perspectives and progress
53. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays