Cloning and molecular characterization of two splice variants of a new putative member of the Siglec-3-like subgroup of Siglecs

Biochemical and Biophysical Research Communications

Volumn 284, Issue 4, 2001, Pages 887-899

  Foussias, George ^a,b   Taylor, Steve M ^a   Yousef, George M ^a,b   Tropak, Michael B ^b   Ordon, Michael H ^a   Diamandis, Eleftherios P ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

CD33 like subgroup; Immunoglobulin superfamily; New gene discovery; Positional cloning; Sialoadhesins; Siglec gene family

Indexed keywords

CD33 ANTIGEN; MEMBRANE PROTEIN; NUCLEOTIDE; SIGLEC 7; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CHROMOSOMAL LOCALIZATION; CHROMOSOME 19Q; DNA FLANKING REGION; EXON; GENE EXPRESSION; GENE MAPPING; GENE STRUCTURE; GENETIC CONSERVATION; GENETIC VARIABILITY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; INTRON; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY;

EID: 0034811225     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5052     Document Type: Article

References (45)

1. Sialoadhesin and related cellular recognition molecules of the immunoglobulin superfamily
2. Siglecs: A family of sialic-acid binding lectins
3. Sialoadhesin, a macrophage sialic acid binding receptor for haemopoietic cells with 17 immunoglobulin-like domains
4. The B-cell antigen CD22 mediates monocyte and erythrocyte adhesion
5. Isolation of a cDNA encoding CD33, a differentiation antigen of myeloid progenitor cells
6. The sialoadhesin CD33 is a myeloid-specific inhibitory receptor
7. Modifications of cell surface sialic acids modulate cell adhesion mediated by sialoadhesin and CD22
8. Myelin associated glycoprotein modulates glia-axon contact in vivo
9. Characterization of siglec-5, a novel glycoprotein expressed on myeloid cells related to CD33
10. OB-BP1/Siglec-6. A leptin- and sialic acid-binding protein of the immunoglobulin superfamily
11. Identification and molecular cloning of p75/AIRM1, a novel member of the sialoadhesin family that functions as an inhibitory receptor in human natural killer cells
12. Identification and characterization of a novel Siglec, Siglec-7, expressed by human natural killer cells and monocytes
13. Siglec-8. A novel eosinophil-specific member of the immunoglobulin superfamily
14. Identification and molecular characterization of a novel member of the Siglec family (SIGLEC9)
15. Cloning, characterization and phylogenetic analysis of Siglec-9, a new member of the CD33-related group of Siglecs. Evidence for co-evolution with sialic acid synthesis pathways
16. Siglec-9. A novel sialic acid binding member of the immunoglobulin superfamily expressed broadly on human blood leukocytes
17. A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1
18. Immunoreceptor tyrosine-based inhibition motifs
19. Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene
20. The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM
21. A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules
22. Inhibition of antigen-induced T cell response and antibody-induced NK cell cytotoxicity by NKG2A: Association of NKG2A with SHP-1 and SHP-2 protein-tyrosine phosphatases
23. The SH2 domain containing inositol 5-phosphatase SHIP2 associates to the immunoreceptor tyrosine-based inhibition motif of Fc gammaRIIB in B cells under negative signaling
24. The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2
25. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
26. Gene recognition by combination of several gene-finding programs
27. Multiple sequence alignment with Clustal X
28. TMbase - A database of membrane spanning protein segments
29. A simple method for displaying the hydropathic character of a protein
30. Prostase/KLK-L1 is a new member of the human kallikrein gene family, is expressed in prostate and breast tissues, and is hormonally regulated
31. An integrated metric physical map of human chromosome 19
32. Quantification analysis of 5′-splice signal sequences in mRNA precursors. Mutations in 5′-splice signal sequence of human beta-globin gene and beta-thalassemia
33. An analysis of vertebrate mRNA sequences: Intimations of translational control
34. The myelin-associated glycoproteins: Membrane disposition, evidence of a novel disulfide linkage between immunoglobulin-like domains, and posttranslational palmitylation
35. Localization of the putative sialic acid-binding site on the immunoglobulin superfamily cell-surface molecule CD22
36. Crystal structure of the N-terminal domain of sialoadhesin in complex with 3′ sialyllactose at 1.85 A resolution
37. The human apolipoprotein C-II gene sequence contains a novel chromosome 19-specific minisatellite in its third intron
38. Engagement of p75/AIRM1 or CD33 inhibits the proliferation of normal or leukemic myeloid cells
39. Differences in the frequency of normal and clonal precursors of colony-forming cells in chronic myelogenous leukemia and acute myelogenous leukemia
40. Expression of normal myeloid-associated antigens by acute leukemia cells
41. A monoclonal antibody reactive with normal and leukemic human myeloid progenitor cells
42. A phase I trial of humanized monoclonal antibody HuM195 (anti-CD33) with low-dose interleukin 2 in acute myelogenous leukemia
43. Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: A phase I study of an anti-CD33 calicheamicin immunoconjugate
44. The immunoglobulin superfamily - Domains for cell surface recognition