Reduction of Cre recombinase toxicity in proliferating Drosophila cells by estrogen-dependent activity regulation

Development Genes and Evolution

Volumn 211, Issue 8-9, 2001, Pages 458-465

  Heidmann, D ^a   Lehner, C F ^a  

^a UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

Chromosomal aberration; Clones; Cre recombinase; loxP; Toxicity

Indexed keywords

BETA GALACTOSIDASE; CRE RECOMBINASE; ESTROGEN; ESTROGEN RECEPTOR; GENE PRODUCT; LIGAND;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ESTROGEN ACTIVITY; GENETIC ANALYSIS; GENETIC MODEL; GENETIC RECOMBINATION; LIGAND BINDING; MAMMAL CELL; MOLECULAR CLONING; MOSAICISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; TISSUE SPECIFICITY; TRANSGENE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; ATTACHMENT SITES, MICROBIOLOGICAL; CELL DIVISION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ESTRADIOL; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INTEGRASES; MUTAGENESIS, SITE-DIRECTED; ORGAN SPECIFICITY; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; TRANSGENES; VIRAL PROTEINS; WING;

EID: 0034811154     PISSN: 0949944X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004270100167     Document Type: Article

References (21)

1. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye
2. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
3. Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings
4. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye
5. The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome
6. Stoichiometry of the Cre recombinase bound to the lox recombining site
7. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
8. Cre recombinase: The universal reagent for genome tailoring
9. Efficient gene activation in cultured mammalian cells mediated by FLP recombinase-expressing recombinant adenovirus
10. FLP recombinase/estrogen receptor fusion proteins require the receptor D domain for responsiveness to antagonists, but not agonists
11. Microdissection and cloning of the white locus and the 3B1-3C2 region of the Drosophila X chromosome
12. Gal4 in the Drosophila female germline
13. Identification of cryptic lox sites in the yeast genome by selection for Cre-mediated chromosome translocations that confer multiple drug resistance
14. Multiplex Cre/lox recombination permits selective site-specific DNA targeting to both a natural and an engineered site in the yeast genome
15. Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
16. Transgene coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila
17. Differential mitotic rates and patterns of growth in compartments in the Drosophila wing
18. Specificity of bone morphogenetic protein-related factors: Cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60 A
19. Mammalian genomes contain active recombinase recognition sites
20. Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila
21. Histological techniques for the Drosophila eye