A simple method for chiral separation of ephedrines using (R)-1-naphthylglycine and 3,5-dinitrobenzoic acid as stationary phase

Analytical Letters

Volumn 34, Issue 11, 2001, Pages 1851-1864

  Zhang, Xianhua ^a   Ouyang, Jin ^a   Yang, Yiping ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Enantiomers separation; Ephedrine; Norephedrine; Pirkle type chiral stationary phase; Pseudoephedrine

Indexed keywords

1 NAPHTHYLGLYCINE; 1,2 DICHLOROETHANE; 3,5 DINITROBENZOIC ACID; CENTRAL STIMULANT AGENT; EPHEDRINE DERIVATIVE; GLYCINE DERIVATIVE; HEXANE; METHANOL; NITROBENZOIC ACID DERIVATIVE; NOREPHEDRINE; PSEUDOEPHEDRINE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHIRALITY; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRUCTURE ANALYSIS; TEMPERATURE;

EID: 0034810665     PISSN: 00032719     EISSN: None     Source Type: Journal    
DOI: 10.1081/AL-100106116     Document Type: Article

References (12)

1. Resolution of the enantiomers of ephedrines using (+)-FLEC chiral derivatization and reversed-phase liquid chromatography
2. Enantiomeric derivatization for biomedical chromatography
3. Separation of enantiomeric ephedrine and pseudoephedrine high pressure liquid chromatography and capillary electrophoresis
4. Chiral determination of amphetamine and related compounds using chloroformates for derivatization and high performance liquid chromatography
5. Enantiomeric separation of amphetamine, methamphetamine and ring substance amphetamines by means of β-cyclodextrin-chiral stationery phase
6. Use of cyclodextrins and cyclodextrin derivatives in high performance liquid chromatography and capillary electrophoresis
7. Enantiomeric differentiation of a wide range of pharmacologically active substances by capillary electrophoresis using modified β-cyclodextrins
8. Enantiomeric separation of amphetamine related drugs by capillary zone electrophoresis using native and derivatized β-cyclodextrin as chiral additives
9. 1-acid glycoprocess-bonded stationery phase
10. Solid-phase reagent containing the 3,5-dinitrophenyl tag for the improved derivatization of chiral and achiral amines, amino alcohols and amino acids in high-performance liquid chromatography with ultraviolet detection
11. Simultaneous chiral analysis of methamphetamine and related compounds by capillary electrophoresis
12. Chiral resolution of enantiomeric steroids by high-performance liquid chromatography on amylose tris(3,5-dimethylphenylcarbamate) under reversed-phase conditions