Progression to large B-cell lymphoma in splenic marginal zone lymphoma: A description of a series of 12 cases

American Journal of Surgical Pathology

Volumn 25, Issue 10, 2001, Pages 1268-1276

  Camacho, F I ^a   Mollejo, M ^a   Mateo, M S ^a   Algara, P ^a   Navas, C ^a   Hernandez J M ^a   Santoja, C ^a   Sole F ^a   Sanchez Beato M ^a   Piris, M A ^a  

^a Invest Oncol Carlos III Ctr Nac   (Spain)

Author keywords

7q deletion; BCL6; IgH; Immunohistochemistry; Large B cell lymphoma; P16INK4a; P53; Splenic marginal zone lymphoma

Indexed keywords

ARTICLE; B CELL LYMPHOMA; CANCER STAGING; GENE DELETION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LARGE CELL CARCINOMA; LYMPHOPROLIFERATIVE DISEASE; MALIGNANT TRANSFORMATION; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SPLEEN CELL; TUMOR LOCALIZATION;

ADULT; AGED; ALLELES; ANTIGENS, NUCLEAR; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 7; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; LYMPHOMA, B-CELL; LYMPHOMA, LARGE-CELL; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-6; SPLENIC NEOPLASMS; SURVIVAL RATE; TRANSCRIPTION FACTORS; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034810658     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200110000-00007     Document Type: Article

References (47)

1. Histologic conversion in non-Hodgkin's lymphomas
2. Mantle cell lymphoma: A clinicopathologic study of 80 cases
3. Poor prognosis in non-villous splenic marginal zone cell lymphoma is associated with p53 mutations
4. Non-MALT marginal zone B-cell lymphomas: A description of clinical presentation and outcome in 124 patients
5. Numerical cytogenetic abnormalities of chromosomes 3, 7, and 12 in marginal zone B-cell lymphomas
6. Recurring chromosomal abnormalities in non-Hodgkin's lymphoma: Biologic and clinical significance
7. Cytogenetic analysis of 363 consecutively ascertained diffuse large B-cell lymphomas
8. Blastic transformation of splenic marginal zone B-cell lymphoma
9. Analysis of the p53, RB/D13S25, and p16 tumor suppressor genes in marginal zone B-cell lymphoma: An interphase fluorescence in situ hybridization study
10. p53 mutations in mantle cell lymphoma are associated with variant cytology and predict a poor prognosis
11. The incidence of trisomy 3 in splenic lymphoma with villous lymphocytes: A study by FISH
12. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
13. Immunoglobulin V genes and CD38 expression in CLL
14. A revised European-American classification of lymphoid neoplasms: A proposal from the international lymphoma study group
15. The World Health Organization Classification of Hematological Malignancies Report of the clinical Advisory Committee Meeting, Airlie House, Virginia, November 1997
16. The natural history of initially untreated low-grade non-Hodgkin' s lymphomas
17. Splenic marginal zone lymphoma
18. Tracing B cell development in human germinal centres by molecular analysis of single cells picked from histological sections
19. Splenic marginal zone lymphoma with increased number of blasts: An aggressive variant?
20. 7q31-32 allelic loss is a frequent finding in splenic marginal zone lymphoma
21. Molecular heterogeneity of splenic marginal zone lymphomas: Analysis of mutations in the 5′ non-coding region of the BCL6 gene
22. Analysis of the frequency of microsatellite instability and p53 gene mutation in splenic marginal zone and MALT lymphomas
23. Splenic marginal zone lymphoma: A distinctive type of low-grade B-cell lymphoma: A clinicopathological study of 13 cases
24. Antigen expression and polymerase chain reaction amplification of mantle cell lymphoma
25. Splenic lymphoma with villous lymphocytes: Natural history and response to therapy in 50 cases
26. Mantle cell lymphoma: Natural history defined in a serially biopsied population over a 20-year period
27. Cytogenetic studies in splenic lymphoma with villous lymphocytes
28. Low-grade B-cell lymphomas of the splenic marginal zone: A clinicopathological and immunohistochemical study of 14 cases
29. INK4a gene inactivation by deletions, mutations, and hypermethylation is associated with transformed and aggressive variants of non-Hodgkin's lymphomas
30. The morphology and immunohistology of splenic involvement by small B-cell lymphomas other than SMZL
31. Richter's syndrome: A report of 39 patients
32. p53 mutation is associated with progression in follicular lymphomas
33. Splenic marginal zone cell lymphoma
34. Splenic marginal zone B-cell lymphomas: Two cytogenetic subtypes, one with gain of 3q and the other with loss of 7q
35. Frequent involvement of chromosomes 1, 3, 7 and 8 in splenic marginal zone B-cell lymphoma
36. Detection of occult follicular lymphoma by specific DNA amplification
37. Variant Philadelphia translocations in chronic myeloid leukemia: Correlation with cancer breakpoints, fragile sites and oncogenes
38. Splenic lymphoma with circulating villous lymphocytes: Report of seven cases and review of the literature
39. Monoclonality in B-lymphoproliferative disorders detected at the DNA level
40. Splenic lymphoma with villous lymphocytes: Clinical presentation, biology, and prognostic factors in a series of 100 patients
41. Splenic marginal zone lymphoma with or without plasmacytic differentiation
42. WAF1/CIP1 and MDM2 expression in non-Hodgkin's lymphoma and their relationship to p53 status: A p53+, MDM2-, p21- immunophenotype associated with missense p53 mutations
43. Loss of p16/INK4A protein expression in non-Hodgkin's lymphomas is a frequent finding associated with tumoral progression
44. Splenic marginal zone cell lymphoma: An immunophenotypic and molecular study of five cases
45. Acute myelomonocytic leukemia with bone marrow eosinophilia and inv(16)(p13q22),t(1;16) (q32;q22)
46. Mutational and functional analyses reveal that ST7 is highly conserved tumor-suppressor gene on human chromosome 7q31