Role of the dopamine transporter and the sodium channel in the cocaine-like discriminative stimulus effects of local anesthetics in rats

Psychopharmacology

Volumn 157, Issue 3, 2001, Pages 260-268

  Wilcox, Kristin M ^a   Paul, Ian A ^a   Ordway, Gregory A ^a   Woolverton, William L ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Dopamine transporter; Drug discrimination; Local anesthetics; Sodium channel

Indexed keywords

CHLOROPROCAINE; COCAINE; DIMETHOCAINE; DOPAMINE TRANSPORTER; LIDOCAINE; PROCAINE; SODIUM CHANNEL; TETRACAINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CAUDATE NUCLEUS; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; DOPAMINE UPTAKE; DOSE RESPONSE; DRUG DISCRIMINATION; DRUG EFFECT; DRUG POTENCY; FRONTAL CORTEX; INHIBITION KINETICS; MALE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RAT;

ANESTHETICS, LOCAL; ANIMALS; COCAINE; DISCRIMINATION (PSYCHOLOGY); DISCRIMINATION LEARNING; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 0034808964     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100796     Document Type: Article

References (37)

1. Effects of stimulation and blockade of dopamine receptor subtypes on the discriminative stimulus properties of cocaine
2. Stimulus generalization from cocaine to analogs with high in vitro affinity for dopamine uptake sites
3. Factors regulating drug cue sensitivity: Limits of discriminability and the role of a progressively decreasing training dose in cocaine-saline discrimination
4. Discriminative stimulus properties of cocaine: Neuropharmacological characteristics as derived from stimulus generalization experiments
5. 3H]batrachotoxinin-A 20α-benzoate binding in vesicular preparation from guinea pig cerebral cortex
6. The discriminative stimulus properties of cocaine in rhesus monkeys
7. Discriminative stimulus properties of cocaine in pigeons
8. Cocaine-like discriminative stimulus effects of procaine, dimethocaine and lidocaine in rats
9. Bidirectional microdialysis in vivo shows dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion
10. Discriminative stimulus effects of drugs: Relationship to abuse potential
11. Comparative stimulus properties of cocaine and other local anesthetics in rats
12. Comparison of the effects of cocaine and other inhibitors of dopamine uptake in rat striatum, nucleus accumbens, olfactory tubercle, and medial prefrontal cortex
13. Differential relationships among dopamine transporter affinities and stimulant potencies of various uptake inhibitors
14. Discriminative stimulus properties of cocaine: Effects of apomorphine, haloperidol, procaine and other drugs
15. Dopamine-independent action of cocaine on striatal and accumbal neurons
16. The half-life of 2-chloroprocaine
17. Relationship between the discriminative stimulus effects and plasma concentrations of intramuscular cocaine in rhesus monkeys
18. Discriminative stimulus effects of esteratic local anesthetics in squirrel monkeys
19. The role of dopamine in the discriminative properties of cocaine
20. 3H]Batrachotoxinin-A 20α-benzoate binding to voltage-sensitive sodium channels: A rapid and quantitative assay for local anesthetic activity in a variety of drugs
21. Cocaine discrimination: Relationship to local anesthetics and monoamine uptake inhibitors in C57BL/6 mice
22. 3H]batrachotoxinin-A 20α-benzoate to sodium channels by local anesthetics
23. 3H]batrachotoxinin-A 20α-benzoate binding sites on sodium channels in mouse brain synaptosomes
24. Cocaine receptors on dopamine transporters are related to self-administration of cocaine
25. Cocaine and GBR 12909 produce equivalent motoric reponses at different occupancy of the dopamine transporter
26. Discriminative stimulus effects of ethyl-B-carboline-3-carboxylate at two training doses in rats
27. Drug discrimination analysis of midazolam under a three-lever procedure II: Differential effects of benzodiazepine receptor agonists
28. Discriminative characteristics of high and low cocaine administration: Effects of psychomotor stimulants
29. Pharmacokinetics of intravenous procaine infusion in humans
30. Comparison of cocaine and procaine discriminative stimuli
31. Noradrenergic involvement in the discriminative stimulus effects of cocaine in squirrel monkeys
32. The discriminative stimulus effects of diazepam in rats at two training doses
33. Pharmacological characterization of the novel discriminative stimulus effects a low dose of cocaine
34. Comparison between dopamine transporter affinity and self-administration potency of local anesthetics in rhesus monkeys
35. In vitro and in vivo effects of cocaine and selected local anesthetics on the dopamine transporter
36. Neurobiology of cocaine abuse
37. Discriminative stimulus effects of morphine: Effects of training dose on agonist and antagonist effects of mu opioids