Inhibition of cyclooxygenase-2 attenuates urinary prostanoid excretion without affecting renal renin expression

Pflugers Archiv European Journal of Physiology

Volumn 442, Issue 6, 2001, Pages 842-847

  Kammerl, Martin C ^a   Nüsing, Rolf M ^b   Seyberth, Hannsjörg W ^b   Riegger, Günter A J ^a   Kurtz, Armin ^a   Krämer, Bernhard K ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

ACE inhibition; Cyclooxygenase 2; Kidney; Low salt diet; Prostaglandins; Rat; Renin; Rofecoxib

Indexed keywords

CYCLOOXYGENASE 2; PROSTANOID; RAMIPRIL; RENIN; ROFECOXIB;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; KIDNEY CORTEX; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN RELEASE; SODIUM INTAKE; URINARY EXCRETION;

6-KETOPROSTAGLANDIN F1 ALPHA; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DIET, SODIUM-RESTRICTED; DINOPROSTONE; GENE EXPRESSION; ISOENZYMES; KIDNEY CORTEX; KIDNEY MEDULLA; LACTONES; MALE; MEMBRANE PROTEINS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; RAMIPRIL; RATS; RATS, SPRAGUE-DAWLEY; RENIN; SULFONES;

EID: 0034807010     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100616     Document Type: Article

References (30)

1. Expression and localization of COX-2 in rodent kidney under normal and experimental conditions
2. Rofecoxib [Vioxx, MK-0966; 4-(4′-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: A potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles
3. Angiotensin II attenuates renal cortical cyclooxygenase-2 expression
4. Genetic deletion of COX-2 prevents increased renin expression in response to ACE inhibition
5. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
6. Differential effects of kinase inhibitors on erythropoietin and vascular endothelial growth factor gene expression in rat hepatocytes
7. Chronic cyclooxygenase-2 inhibition blunts low sodium-stimulated renin without changing renal haemodynamics
8. Cyclooxygenase-2 mediates increased renal renin content induced by low-sodium diet
9. Cyclooxygenase-2 in kidney development
10. Cyclooxygenase-2 in the kidney
11. Cyclooxygenase-2 is associated with the macula densa of rat kidney and increases with salt restriction
12. Coordinate expression of cyclooxygenase-2 and renin in the rat kidney in renovascular hypertension
13. Regulation of renal prostaglandin receptors
14. Differential regulation of renal cyclooxygenase mRNA by dietary salt intake
15. Prostaglandins stimulate renin secretion and renin mRNA in mouse renal juxtaglomerular cells
16. Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity
17. Localization of cyclooxygenase-1 and -2 in adult and fetal human kidney: Implication for renal function
18. Acute upregulation of COX-2 by renal artery stenosis
19. Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: Identification of 4-[5-(4-methyl-phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib)
20. Renal changes induced by a cyclooxygenase-2 inhibitor during normal and low sodium intake
21. Renal effects of selective cyclooxygenase-2 inhibition in normotensive salt-depleted subjects
22. Nitric oxide and prostaglandins are involved in the macula densa control of the renin system
23. The role of angiotensin II in the feedback control of renin gene expression
24. Determination of seven prostanoids in 1 ml of urine by gas chromatography-negative ion chemical ionization triple stage quadrupole mass spectrometry
25. Cyclooxygenase-2 inhibition decreases renin content and lowers blood pressure in a model of renovascular hypertension
26. A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats
27. Inhibition of the renin-angiotensin system up-regulates cyclooxygenase-2 expression in the macula densa
28. Renin expression in COX-2-knockout mice on normal or low-salt diets
29. Regulation of cyclooxygenase expression in the kidney by dietary salt intake
30. Regulation of cyclooxygenase-2 (COX-2) in rat renal cortex by adrenal glucocorticoids and mineralocorticoids