Manifold reduction of moesin in fetal Down syndrome brain

Biochemical and Biophysical Research Communications

Volumn 286, Issue 5, 2001, Pages 1191-1194

  Lubec, B ^a   Weitzdoerfer, R ^a   Fountoulakis, M ^b  

^a UNIVERSITY OF VIENNA   (Austria)

^b Preclinical Neurosciences   (Switzerland)

Author keywords

Down syndrome; ERM family; Ezrin; Fetal; Moesin; Radixin; Trisomy 21

Indexed keywords

DREBRIN; EZRIN; F ACTIN; MOESIN; RADIXIN;

AMINO ACID SEQUENCE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN LEVEL; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; FETUS; GEL ELECTROPHORESIS; HUMAN; HUMAN TISSUE; MALE; MASS SPECTROMETRY; NERVE CELL; NERVE FIBER GROWTH; PRIORITY JOURNAL; PROTEIN EXPRESSION; SECOND TRIMESTER PREGNANCY;

EID: 0034805986     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5520     Document Type: Article

References (27)

1. Regulation of cortical structure by the ezrin-radixin-moesin protein family
2. ERM proteins in cell adhesion and membrane dynamics
3. ERM (ezrin, radixin, moesin) family: From cytoskeleton to signal transduction
4. Structural diversity of band 4.1 superfamily members
5. Membrane-actin microfilament connections: An increasing diversity of players related to band 4.1
6. Ezrin: A protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structures
7. Suppression of Radixin and Moesin alters growth cone morphology, motility and process formation in primary cultured neurons
8. Rho- and Rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: An essential role for ezrin/radixin/moesin proteins
9. Association of the myosin-binding subunit of myosin phosphatase and moesin: Dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase
10. Normal development of mice and unimpaired cell adhesion/cell motility/actin-based cytoskeleton without compensatory up-regulation of ezrin or radixin in moesin gene knockout
11. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
12. Effect of protein application mode and acrylamide concentration on the resolution of protein spots separated by two-dimensional gel electrophoresis
13. Identification of proteins by matrix-assisted laser desorption ionisation-mass spectrometry following in-gel digestion in low-salt, non-volatile buffer and simplified peptide recovery
14. Reliable automatic protein identification from matrix-assisted laser desorption/ionisation mass spectrometric peptide fingerprints
15. The role of cytoskeleton in organizing growth cones: A microfilament-associated growth cone component depends upon microtubules for itsnlocalization
16. Dendritic atrophy in children with Down syndrome
17. Growth and development of the brain in Down syndrome
18. The metabolic and molecular bases of inherited disease
19. Abnormal neurogenesis and synaptogenesis in Down syndrome brain
20. Aberrant expression of dihydropyrimidinase related proteins-2, -3 and -4 in fetal Down syndrome brain
21. Fetal life in Down syndrome starts with normal neuronal density but impaired dendritic spines and synaptosomal structure
22. Detection of actin cleavage in Alzheimer's disease
23. Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease
24. Moesin, the major ERM protein of lymphocytes and platelets, differs from ezrin in its intensitivity to calpain
25. Ezrin-calpain I interactions in gastric parietal cells
26. MIR is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth
27. Impairment of cell adhesion by expression of the mutant neurofibomatosis type 2 (NF2) genes which lack exons in the ERM-homology domain Oncogene