In vivo synthesis of the periplasmic domain of TonB inhibits transport through the FecA and FhuA iron siderophore transporters of Escherichia coli

Journal of Bacteriology

Volumn 183, Issue 20, 2001, Pages 5885-5895

  Peter Howard, S ^a   Herrmann, C ^a   Stratillo, C W ^a   Braun, V ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; FERRICHROME; HYBRID PROTEIN; IRON; MEMBRANE PROTEIN; OUTER MEMBRANE PROTEIN; PROTEIN TONB; SIDEROPHORE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIOPHAGE; BINDING COMPETITION; CELL KILLING; CYTOPLASM; ESCHERICHIA COLI; GENE INDUCTION; GENE OVEREXPRESSION; GROWTH INHIBITION; INTRACELLULAR TRANSPORT; IRON TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN SYNTHESIS; PROTON MOTIVE FORCE;

BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BACTERIOPHAGES; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; CITRIC ACID; COLICINS; CULTURE MEDIA; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FERRICHROME; GENE EXPRESSION REGULATION, BACTERIAL; IRON; MEMBRANE PROTEINS; OPERON; PEPTIDE FRAGMENTS; PERIPLASM; PROTEIN SORTING SIGNALS; RECEPTORS, CELL SURFACE; RECEPTORS, VIRUS; RECOMBINANT FUSION PROTEINS; SIDEROPHORES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0034805380     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.20.5885-5895.2001     Document Type: Article

References (48)

1. The wild-type allele of tonB in Escherichia coli is dominant over the tonB1 allele, encoding TonBQ160K, which suppresses the btuB451 mutation
2. Genetic suppression demonstrates interaction of TonB protein with outer membrane transport proteins in Escherichia coli
3. Specific in vivo labeling of cell surface-exposed protein loops: Reactive cysteines in the predicted gating loop mark a ferrichrome binding site and a ligand-induced conformational change of the Escherichia coli FhuA protein
4. The proton motive force drives the outer membrane transport of cobalamin in Escherichia coli
5. The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity
6. Surface signaling: Novel transcription initiation mechanism starting from the cell surface
7. Evolutionary relationship of uptake systems for biopolymers in Escherichia coli: Crosscomplementation between the TonB-ExbB-ExbD and the TolA-TolQ-TolR proteins
8. The β-barrel domain of FhuAΔ5-160 is sufficient for TonB-dependent FhuA activities of Escherichia coli
9. Crystal structure of the outer membrane active transporter FepA from Escherichia coli
10. Crystal structure of the dimeric domain of TonB reveals a novel fold
11. Site-directed disulfide bonding reveals an interaction site between energy-coupling protein TonB and BtuB, the outer membrane cobalamin transporter
12. Transcription of the region encoding the ferric dicitrate-transport system in Eschetichia coli: Similarity between promoters for fecA and for extracytoplasmic function signa factors
13. Surface signaling in ferric citrate transport gene induction: Interaction of the FecA, FecR, and FecI regulatory proteins
14. Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide
15. Involvement of ExbB and TonB in transport across the outer membrane of Escherichia coli: Phenotypic complementation of exb mutants by overexpressed tonB and physical stabilization of TonB by ExbB
16. Studies in transformation of Escherichia coli with plasmids
17. Functional interaction of the tonA/tonB receptor system in Escherichia coli
18. Signal transfer through three compartments: Transcription initiation of the Escherichia coli ferric citrate transport system from the cell surface
19. Suppression of the btuB451 mutation by mutations in the tonB gene suggests a direct interaction between TonB and TonB-dependent receptor proteins in the outer membrane of Escherichia coli
20. Interactions in the TonB-dependent energy transduction complex: ExbB and ExbD form homomul-timers
21. Role of the TonB amino terminus in energy transduction between membranes
22. Mutual inhibition of cobalamin and siderophore uptake systems suggests their competition for TonB function
23. A sequence-specific function for the N-terminal signallike sequence of the TonB protein
24. An aspartate deletion mutation defines a binding site of the multifunctional FhuA outer membrane receptor of Escherichia coli K-12
25. Transcription induction of the ferric citrate transport genes via the N-terminus of the FecA outer membrane protein, the Ton system and the electrochemical potential of the cytoplasmic membrane
26. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
27. Regions of Escherichia coli TonB and FepA proteins essential for in vivo physical interactions
28. Protonmotive force, ExbB and ligand-bound FepA drive confomational changes in TonB
29. The conserved proline-rich motif is not essential for energy transduction by Escherichia coli TonB protein
30. TonB protein appears to transduce energy by shuttling between the cytoplasmic membrane and the outer membrane in Escherichia coli
31. Transmembrane signaling across the ligand-gated FhuA receptor: Crystal structures of free and ferrichrome-bound states reveal allosteric changes
32. Oligomeric states and siderophore binding of the ligand-gated FhuA protein that forms channels across Escherichia coli outer membranes
33. Reduced activity of TonB-dependent functions in strains of Escherichia coli
34. Substrate-induced exposure of an energy-coupling motif of a membrane transporter
35. Characterization of in vitro interactions between a truncated TonB protein from Escherichia coli and the outer membrane receptors FhuA and FepA
36. Cell envelope signaling in Escherichia coli
37. Ligand-induced conformational change in the ferrichrome-iron receptor of Escherichia coli K-12
38. Domains of colicin M involved in uptake and activity
39. Aerobic regulation of the Escherichia coli tonB gene by changes in iron availability and the fur locus
40. DNA sequencing with chain-terminating inhibitors
41. Transport across the outer membrane of Escherichia coli K-12 via the FhuA receptor is regulated by the TonB protein of the cytoplasmic membrane
42. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes
43. fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB
44. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
45. Activity domains of the TonB protein
46. Novel two-component transmembrane transcription control: Regulation of iron dicitrate transport in Escherichia coli K-12
47. Preparation of the periplasmic binding proteins from Salmonella typhimurium and Escherichia coli