Interactions in the TonB-dependent energy transduction complex: ExbB and ExbD form homomultimers

Journal of Bacteriology

Volumn 180, Issue 22, 1998, Pages 6031-6038

  Higgs, Penelope I ^a   Myers, Paul S ^a,b   Postle, Kathleen ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b Millennium Biotherapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN;

ACTIVE TRANSPORT; ARTICLE; ENERGY TRANSFER; ESCHERICHIA COLI; IRON TRANSPORT; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0031791530     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/jb.180.22.6031-6038.1998     Document Type: Article

References (48)

1. Ahmer, B., and K. Postle. Unpublished data.
2. Ahmer, B. M. M., M. G. Thomas, R. A. Larsen, and K. Postle. 1995. Characterization of the exbBD operon of Escherichia coli and the role of ExbB and ExbD in TonB function and stability. J. Bacteriol. 177:4742-4747.
3. Bell, P. E., C. D. Nau, J. T. Brown, J. Konisky, and R. J. Kadner. 1990. Genetic suppression demonstrates direct interaction of TonB protein with outer membrane transport proteins in Escherichia coli. J. Bacteriol. 172: 3826-3829.
4. Biswas, G. D., J. E. Anderson, and P. F. Sparling. 1997. Cloning and functional characterization of Neisseria gonorrhoeae tonB, exbB and exbD genes. Mol. Microbiol. 24:169-179.
5. Bradbeer, C. 1993. The proton motive force drives the outer membrane transport of cobalamin in Escherichia coli. J. Bacteriol. 175:3146-3150.
6. Braun, V. 1995. Energy-coupled transport and signal transduction through the gram-negative outer membrane via TonB-ExbB-ExbD-dependent receptor proteins. FEMS Microbiol. Rev. 16:295-307.
7. Braun, V. 1989. The structurally related exbB and tolQ genes are interchangeable in conferring tonB-dependent colicin, bacteriophage, and albomycin sensitivity. J. Bacteriol. 171:6387-6390.
8. Braun, V., S. Gaisser, C. Herrman, K. Kampfenkel, H. Killman, and I. Traub. 1996. Energy-coupled transport across the outer membrane of Escherichia coli: ExbB binds ExbD and TonB in vitro, and leucine 132 in the periplasmic region and aspartate 25 in the transmembrane region are important for ExbD activity. J. Bacteriol. 178:2836-2845.
9. Braun, V., K. Günter, and K. Hantke. 1991. Transport of iron across the outer membrane. Biol. Metals 4:14-22.
10. Eick-Helmerich, K., and V. Braun. 1989. Import of biopolymers into Escherichia coli: nucleotide sequences of the exbB and exbD genes are homologous to those of the tolQ and tolR genes, respectively. J. Bacteriol. 171:5117-5126.
11. Eick-Helmerich, K., K. Hantke, and V. Braun. 1987. Cloning and expression of the exbB gene of Escherichia coli K-12. Mol. Gen. Genet. 206:246-251.
12. Fischer, E., K. Günter, and V. Braun. 1989. Involvement of ExbB and TonB in transport across the outer membrane of Escherichia coli: phenotypic complementation of exb mutants by overexpressed tonB and physical stabilization of TonB by ExbB. J. Bacteriol. 171:5127-5134.
13. Günter, K., and V. Braun. 1990. In vivo evidence for FhuA outer membrane receptor interaction with the TonB inner membrane protein from Escherichia coli. FEBS Lett. 274:85-88.
14. Gutermann, S. K., and L. Dann. 1973. Excretion of enterochelin by exbA and exbB mutants of Escherichia coli. J. Bacteriol. 114:1225-1230.
15. Heller, K. J., R. J. Kadner, and K. Günter. 1988. Suppression of the btuB451 mutation by mutations in the tonB gene suggests a direct interaction between TonB and TonB-dependent receptor proteins in the outer membrane of Escherichia coli. Gene 64:147-153.
16. Howard, S. P., H. G. Meiklejohn, D. Shivak, and R. Jahagirdar. 1996. A TonB-like protein and a novel membrane protein containing an ATP-binding cassette function together in exotoxin secretion. Mol. Microbiol. 22:595-604.
17. Jarosik, G. P., I. Maciver, and E. J. Hansen. 1995. Utilization of transferrin-bound iron by Haemophilus influenzae requires an intact tonB gene. Infect. Immun. 63:710-713.
18. Jarosik, G. P., J. D. Sanders, L. D. Cope, U. Muller-Eberhard, and E. J. Hansen. 1994. A functional tonB gene is required for both utilization of heme and virulence expression by Haemophilus influenzae type b. Infect. Immun. 62:2470-2477.
19. Jiang, X., M. A. Payne, Z. Cao, S. B. Foster, J. B. Feix, S. C. Newton, and P. E. Klebba. 1997. Ligand-specific opening of a gated porin channel in the outer membrane of living bacteria. Science 276:1261-1264.
20. Kampfenkel, K., and V. Braun. 1992. Membrane topology of the Escherichia coli ExbD protein. J. Bacteriol. 174:5485-5487.
21. Kampfenkel, K., and V. Braun. 1993. Topology of the ExbB protein in the cytoplasmic membrane of Escherichia coli. J. Biol. Chem. 268:6050-6057.
22. Karlsson, M., K. Hannavy, and C. F. Higgins. 1993. ExbB acts as a chaperone-like protein to stabilize TonB in the cytoplasm. Mol. Microbiol. 8:389-396.
23. Larsen, R. A., D. Foster-Hartnett, M. A. McIntosh, and K. Postle. 1997. Regions of Escherichia coli TonB and FepA proteins essential for in vivo physical interactions. J. Bacteriol. 179:3213-3221.
24. Larsen, R. A., P. S. Myers, J. T. Skare, C. L. Seachord, R. P. Darveau, and K. Postle. 1996. Identification of TonB homologs in the family Enterobacteriaceae and evidence for conservation of TonB-dependent energy transduction complexes. J. Bacteriol. 178:1363-1373.
25. Larsen, R. A., M. G. Thomas, and K. Postle. Unpublished data.
26. Larsen, R. A., M. T. Thomas, G. E. Wood, and K. Postle. 1994. Partial suppression of an Escherichia coli TonB transmembrane domain mutation (ΔV17) by a missense mutation in ExbB. Mol. Microbiol. 13:627-640.
27. Larsen, R. A., G. E. Wood, and K. Postle. 1993. The conserved proline-rich motif is not essential for energy transduction by Escherichia coli TonB protein. Mol. Microbiol. 10:943-953.
28. Letain, T. E., and K. Postle. 1997. TonB protein appears to transduce energy by shuttling between the cytoplasmic membrane and the outer membrane in Gram-negative bacteria. Mol. Microbiol. 24:271-283.
29. Matsushiro. A. 1963. Specialized transduction of tryptophan markers in Escherichia coli K-12 by bactcriophage φ80. Virology 19:475-482.
30. Means, G. E., and R. E. Feeney. 1971. Chemical modification of proteins. Holden-Day, Inc., San Francisco, Calif.
31. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
32. Moeck, G. S., J. W. Coulton, and K. Postle. 1997. Cell envelope signaling in Escherichia coli. Ligand binding to the ferrichrome-iron receptor FhuA promotes interaction with the energy-transducing protein TonB. J. Biol. Chem. 272:28391-28397.
33. Postle, K. 1990. TonB and the gram-negative dilemma. Mol. Microbiol. 4:2019-2025.
34. Postle, K. 1993. TonB protein and energy transduction between membranes. J. Bioenerg. Biomembr. 25:591-601.
35. Prossnitz, E., K. Nikaido, S. J. Ulbrich, and G. F.-L. Ames. 1988. Formaldehyde and photoactivatable cross-linking of the periplasmic binding protein to a membrane component of the histidine transport system of Salmonella typhimurium. J. Biol. Chem. 263:17917-17920.
36. Reynolds, P. R., G. P. Mottur, and C. Bradbeer. 1980. Transport of vitamin B12 in Escherichia coli. Some observations on the roles of the gene products of btuC and tonB. J. Biol. Chem. 255:4313-4319.
37. Roof, S. K., J. D. Allard, K. P. Bertrand, and K. Postle. 1991. Analysis of Escherichia coli TonB membrane topology by use of PhoA fusions. J. Bacteriol. 173:5554-5557.
38. Schöffler, H., and V. Braun. 1989. Transport across the outer membrane of Escherichia coli K12 via the FhuA receptor is regulated by the TonB protein of the cytoplasmic membrane. Mol. Gen. Genet. 217:378-383.
39. Singer, M., T. A. Baker, G. Schnitzler, S. M. Deischel, M. Goel, W. Dove, K. J. Jaacks, A. D. Grossman, J. W. Erickson, and C. A. Gross. 1989. A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Esrherichia coli. Microbiol. Rev. 53:1-24.
40. Skare, J. T., B. M. M. Ahmer, C. L. Seachord, R. P. Darveau, and K. Postle. 1993. Energy transduction between membranes - TonB, a cytoplasmic membrane protein, can be chemically cross-linked in vivo to the outer membrane receptor FepA. J. Biol. Chem. 268:16302-16308.
41. Skare, J. T., S. K. Roof, and K. Postle. 1989. A mutation in the amino terminus of a hybrid TrpC-TonB protein relieves overproduction lethality and results in cytoplasmic accumulation. J. Bacteriol. 171:4442-4447.
42. Spudich, J. L. 1998. Variations on a molecular switch: transport and sensory signalling by archaeal rhodopsins. Mol. Microbiol. 28:1051-1058.
43. Stojiljkovic, I., and N. Srinivasan. 1997. Neisseria meningitidis tonB, exbB, and exbD genes: Ton-dependent utilization of protein-bound iron in neisseriae. J. Bacteriol. 179:805-812.
44. Sun, T. P., and R. E. Webster. 1986. fii, a bacterial locus required for filamentous phage infection and its relation to colicin-tolerant tolA and tolB. J. Bacteriol. 165:107-115.
45. Torres, A. G., and S. M. Payne. 1997. Haem iron-transport system in enterohaemorrhagic Escherichia coli O157:H7. Mol. Microbiol. 23:825-833.
46. Towbin, H., T. Staehelin, and J. Gordon. 1979. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Proc. Natl. Acad. Sci. USA 76:4350-4354.
47. Tuckman, M., and M. S. Osburne. 1992. In vivo inhibition of TonB-dependent processes by a TonB box consensus pentapeptide. J. Bacteriol. 174:320-323.
48. Wooldridge, K. G., J. A. Morrisey, and P. H. Williams. 1992. Transport of ferric aerobactin into the periplasm and cytoplasm of Escherichia coli K12: role of envelope-associated proteins and effect of endogenous siderophores. J. Gen. Microbiol. 138:597-603.