Adjuvant radiochemotherapy in high-risk rectal cancer results of a prospective non-randomized study

Tumori

Volumn 87, Issue 4, 2001, Pages 239-247

  Lupattelli, M ^a   Maranzano, E ^a   Bellavita, R ^a   Tarducci, R ^a   Latini, R ^a   Castagnoli, P ^a   Bufalari, A ^a   Corgna, E ^a   Pinaglia, D ^a   Rossetti, R ^a   Ribacchi, R ^a   Latini, P ^a  

^a POLICLINICO MONTELUCE   (Italy)

Author keywords

Chemotherapy; Combined adjuvant therapy; Radiotherapy; Rectal cancer; Stage II III

Indexed keywords

FLUOROURACIL;

ADULT; ARTICLE; BONE MARROW SUPPRESSION; CANCER ADJUVANT THERAPY; CANCER RADIOTHERAPY; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; DRUG EFFECT; DRUG EFFICACY; FEASIBILITY STUDY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HUMAN; ITALY; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PROCTITIS; PROGNOSIS; RADIATION DOSE; RADIATION INJURY; RECTUM ABDOMINOPERINEAL RESECTION; RECTUM ANTERIOR RESECTION; RECTUM CANCER; SURVIVAL RATE;

EID: 0034804666     PISSN: 03008916     EISSN: None     Source Type: Journal    
DOI: 10.1177/030089160108700406     Document Type: Article

References (59)

1. Cancer mortality in Italy, 1993
2. Adjuvant and neoadjuvant treatment of rectal cancer
3. Practice guidelines for colorectal cancer
4. Areas of failure found at re-operation (second or symptomatic look) following "curative surgery" for adenocarcinoma of the rectum: Clinico-pathologic correlation and implications for adjuvant therapy
5. Carcinoma of the colon and rectum: The natural history reviewed in 1704 patients
6. Enhanced survival of patients with colon and rectal cancer is based upon wide anatomic resection
7. Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP protocol R-01
8. Prolongation of the disease-free interval in surgically treated rectal carcinoma
9. Radiation therapy and fiuorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum
10. Patterns of recurrence in adenocarcinoma of the rectum and rectosigmoid treated with surgery alone: Implications in treatment planning with adjuvant radiation therapy
11. Resectable adenocarcinoma of the rectosigmoid and rectum. Patterns of failure and survival
12. Carcinoma of the rectum and rectosigmoid: Cancer specific long-term survival. A series of 1061 cases treated by one surgeon
13. Pattern of pelvic recurrence following definitive resections of rectal cancer
14. Patterns of recurrence of rectal cancer after potentially curative surgery
15. Pathologic, anatomic and biologic factors correlated with local recurrence of colo-rectal cancer
16. Postoperative radiotherapy in Duke'B and C carcinoma of the rectum and rectosigmoid. A randomized multicenter study
17. Survival after postoperative combination treatment of rectal cancer
18. Effective surgical adjuvant therapy for high-risk rectal carcinoma
19. Postoperative radiation therapy for rectal cancer. An interim analysis of a prospective, randomized multicenter trial in the Netherlands
20. Randomized trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum
21. Radical surgery and postoperative radiotherapy as combined treatment in rectal cancer. Final results of a phase III study of the European Organization for Research and Treatment of Cancer
22. National Institutes of Health Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer
23. A prospective study of treatment techniques to minimize the volume of pelvic small bowel with reduction of acute and late effects associated with pelvic irradiation
24. Minimization of small bowel volume within treatment fields utilizing customized "belly board"
25. Radiotherapeutic techniques in rectal cancer
26. Time to loco-regional recurrence after resection of Dukes' B and C colorectal cancer with or without adjuvant postoperative radiotherapy. A multivariate regression analysis
27. Randomized trials of adjuvant radiation therapy for rectal carcinoma. A review
28. Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery
29. Pharmacologic requirements for obtaining sensitization of human tumor cells in vitro to combine 5-fluorouracil for ftorafur and X-rays
30. Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: Initial results of Intergroup 0114
31. Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes' B and C rectal cancer
32. Postoperative radiation and concomitant bolus fluorouracil with or without additional chemotherapy with fluorouracil and high-dose leucovorin in patients with high-risk rectal cancer: A randomized phase III study conducted by the Hellenic Cooperalive Oncology Group
33. Adjuvant radio-chemotherapy in radically resected high risk rectal cancer. Preliminary results of a prospective trial
34. Adjuvant postoperative radiotherapy in rectal cancer: 148 Cases treated at Florence University with 8 year median follow-up
35. Postoperative adjuvant therapy of rectal cancer: An analysis of disease control, survival, and prognostic factors
36. Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection. Cases with or without adjuvant chemotherapy
37. Adjuvant postoperative radiotherapy for adenocarcinoma of the rectum and rectosigmoid. A retrospective analysis of locoregional control, survival, and prognostic factors on 178 patients
38. Prognostic significance of tumor fixation of rectal carcinoma. Implications for adjunctive radiation therapy
39. Adjuvant radiation therapy for rectal carcinoma: Predictors of outcome
40. Adjuvant treatment in the curative management of rectal cancer: A critical review of the results of clinical randomized trials
41. The current role of radiotherapy in colo-rectal cancer
42. The prevention of radiation-induced small bowel complications
43. Late complications of postoperative radiation therapy for cancer of the rectum and rectosigmoid
44. Morbidities of adjuvant chemotherapy and radiotherapy for resectable rectal cancer: An overview
45. Treatment planning for colorectal cancer: Radiation and surgical techniques and value of small-bowel films
46. Results of radical surgery for rectal cancer
47. Mesorectal excision for rectal cancer
48. Designing the optimal surgery for rectal carcinoma
49. Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02
50. Swedish rectal cancer trial. Improved survival with preoperative radiotherapy in resectable rectal cancer
51. Preoperative radiation and chemotherapy in the treatment of adenocarcinoma of the rectum
52. Preliminary results of preoperative 5-fluorouracil, low-dose leucovorin and concurrent radiation therapy for clinically resectable T3 rectal cancer
53. Preoperative infusional chemoradiation therapy for stage T3 rectal cancer
54. Preoperative chemoradiation for extraperitoneal T3 rectal cancer: Acute toxicity, tumor response, sphincter preservation
55. Preoperative radiotherapy is better than postoperative radiotherapy in patients with rectal cancer
56. Chemoradiation with raltitrexed (tomudex) and concomitant preoperative radiotherapy has potential in the treatment of stage II/III resectable rectal cancer
57. Interaction of tomudex with radiation in vitro and in vivo
58. Raltitrexed (tomudex) concomitant with radiotherapy as adjuvant treatment for patients with rectal cancer: Preliminary results of phase I studies