Moderate hypothermia during cardiopulmonary bypass reduces myocardial cell damage and myocardial cell death related to cardiac surgery.

Journal of the American College of Cardiology

Volumn 38, Issue 4, 2001, Pages 1216-1223

  Vazquez Jimenez, Jaime F ^a,c   Qing, Ma ^b   Hermanns, Benita ^c   Klosterhalfen, Bernd ^c   Wöltje, Michael ^d   Chakupurakal, Raj ^b   Schumacher, Kathrin ^b   Messmer, Bruno J ^a   von Bernuth, Götz ^b   Seghaye, Marie Christine ^b  

^a Clinic for Thoracic and Cardiovascular Surgery   (Germany)

^b Pediatric Cardiology   (Germany)

^c UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^d RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; MESSENGER RNA; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; CORRELATION FUNCTION; CYTOKINE PRODUCTION; FEMALE; HEART MUSCLE INJURY; HEART MUSCLE NECROSIS; HEART PROTECTION; HYPOTHERMIA; LYMPH FLOW; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; SWINE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CARDIOPULMONARY BYPASS; CELL DEATH; FEMALE; HEMODYNAMIC PROCESSES; HYPOTHERMIA, INDUCED; IN SITU NICK-END LABELING; INTERLEUKIN-10; MYOCARDIUM; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034800983     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(01)01469-3     Document Type: Article

References (26)

1. Interleukin 6 induction in the canine myocardium after cardiopulmonary bypass
2. Influence of temperature during cardiopulmonary bypass on leukocyte activation, cytokine balance and postoperative organ damage
3. Corticosteroids increase blood interleukin-10 levels during cardiopulmonary bypass in men
4. Tumor necrosis factor in the heart
5. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: A report from the Studies of Left Ventricular Dysfunction (SOLVD)
6. Relationship of the proinflammatory cytokines to myocardial ischemia and dysfunction after uncomplicated coronary revascularization
7. Introduction
8. Human myocardial tissue TNF-alpha expression following acute global ischemia in vivo
9. IL-10 is induced in the reperfused myocardium and may modulate the reaction to injury
10. Cannulation of the cardiac lymphatic system in swine
11. Mechanism of cell death during warm hepatic ischemia-reperfusion in rats: Apoptosis or necrosis?
12. Induction of interleukin-8 expression during cardiopulmonary bypass
13. Cytokines and cardiac contractile function
14. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
15. Ingenuous interpretation of elevated blood levels of macromolecular markers of myocardial injury: A recipe for confusion
16. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
17. Interleukin-10 release related to cardiopulmonary bypass in infants undergoing cardiac operations
18. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding
19. Crucial role of endogenous interleukin-10 production in myocardial ischemia/reperfusion injury
20. Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression
21. Apoptosis in the pathogenesis and treatment of disease
22. Hypothermia causes a reversible, p53-mediated cell cycle arrest in cultured fibroblasts
23. IL-10 induces apoptosis in human monocytes involving the CD95 receptor/ligand pathway
24. IL-10 enhances resolution of pulmonary inflammation in vivo by promoting apoptosis of neutrophils
25. Interleukin-10 counter-regulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis
26. Troponin I degradation and covalent complex formation accompanies myocardial ischemia/reperfusion injury