High dose therapy and autologous hemopoietic stem cell transplantation in rheumatoid arthritis - The feasibility of phase III trials

Journal of Rheumatology

Volumn 28, Issue SUPPL. 64, 2001, Pages 55-59

  Snowden, J ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Clinical trials; Rheumatoid arthritis; Stem cell transplantation

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; METHYLPREDNISOLONE; IMMUNOSUPPRESSIVE AGENT;

AUTOGRAFT; CLINICAL PRACTICE; CLINICAL TRIAL; CONFERENCE PAPER; DISEASE SEVERITY; EVIDENCE BASED MEDICINE; FOLLOW UP; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; STATISTICAL ANALYSIS; AUTOTRANSPLANTATION; CONTROLLED CLINICAL TRIAL; DOSE RESPONSE; FEASIBILITY STUDY; IMMUNOLOGY; IMMUNOSUPPRESSIVE TREATMENT; METHODOLOGY; MULTICENTER STUDY; RANDOMIZED CONTROLLED TRIAL; REVIEW;

ARTHRITIS, RHEUMATOID; CLINICAL TRIALS, PHASE III; DOSE-RESPONSE RELATIONSHIP, DRUG; EVIDENCE-BASED MEDICINE; FEASIBILITY STUDIES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; MULTICENTER STUDIES; RANDOMIZED CONTROLLED TRIALS; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS;

EID: 0034796816     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (21)

1. New opportunities for the treatment of severe autoimmune diseases: Bone marrow transplantation
2. Haemopoietic stem cell transplantation for autoimmune diseases
3. International symposium on stem cell transplantation for autoimmune diseases, Seattle, WA, USA: October 27, 1995
4. Blood and marrow stem cell transplants in autoimmune disease. A consensus report written on behalf of the European League Against Rheumatism (EULAR) and the European Group for Blood and Marrow Transplantation (EBMT)
5. Autologous hematopoietic stem cell transplants in autoimmune diseases - Feasibility and transplant related mortality
6. Hematopoietic stem cell transplantation in rheumatic diseases
7. Autologous stem cell transplantation for rheumatoid arthritis - Interim report of 6 patients
8. A phase I study to address the safety and efficacy of granulocyte colony stimulating factor for the mobilisation of hematopoietic progenitor cells in active rheumatoid arthritis
9. A randomised, blinded, placebo-controlled, dose escalation study of the tolerability and efficacy of filgrastim for haemopoietic stem cell mobilisation in patients with severe active rheumatoid arthritis
10. Intensified-dose cyclophosphamide and granulocyte colony-stimulating factor administration for hematopoietic stem cell mobilization in refractory rheumatoid arthritis
11. High efficiency of hematopoietic progenitor cell mobilisation with cyclophosphamide (CTX) plus G-CSF (but not with G-CSF alone) in patients with severe rheumatoid arthritis
12. Autologous hematopoietic stem cell transplantation in refractory rheumatoid arthritis. Sustained response in two of four patients
13. Remission and immune reconstitution after T-cell-depleted stem-cell transplantation for rheumatoid arthritis
14. Autologous T cell depleted CD34+ peripheral blood stem cell transplantation in four patients with refractory rheumatoid arthritis and juvenile chronic arthritis
15. Autologous bone marrow transplantation for rheumatoid arthritis
16. A phase I/II dose escalation study of intensified cyclophosphamide and autologous blood stem cell rescue in severe, active rheumatoid arthritis
17. Peripheral blood stem cell transplantation for rheumatoid arthritis - The Australian multicentre randomised trial
18. Autologous stem cell transplantation for refractory rheumatoid arthritis
19. Treatment of refractory rheumatoid arthritis utilizing an outpatient autologous blood stem cell transplantation protocol
20. Minimum important differences between patients with rheumatoid arthritis: The patients perspective
21. A practical guide to continuous population based data collection (PACE): A process facilitating uniformity of care and research into practice