Hepatic paraoxonase activity alterations and free radical production in rats with experimental cirrhosis

Metabolism: Clinical and Experimental

Volumn 50, Issue 9, 2001, Pages 997-1000

  Ferre N ^a   Camps, J ^a   Cabre M ^a   Paul, A ^a   Joven, J ^a  

^a HOSPITAL UNIVERSITARI SANT JOAN DE REUS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ARYLDIALKYLPHOSPHATASE; CARBON TETRACHLORIDE; FREE RADICAL; LIPID PEROXIDE; MALONALDEHYDE; ZINC;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; DIET SUPPLEMENTATION; DRUG EFFECT; ENZYME ACTIVITY; EXPERIMENTAL LIVER CIRRHOSIS; IN VITRO STUDY; LIPID PEROXIDATION; LIVER FUNCTION; LIVER INJURY; LIVER MICROSOME; LIVER PROTECTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0034794043     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1053/meta.2001.25589     Document Type: Article

References (23)

1. Human serum paraoxonase/arylesterase
2. Structural and functional diversity of paraoxonases
3. Paraoxonase: Biochemistry, genetics and relationship to plasma lipoproteins
4. Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low-density lipoprotein
5. HDL, its enzymes and its potential to influence lipid peroxidation
6. Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase
7. Rat liver paraoxonase: Subcellular distribution and characterization
8. Human liver paraoxonase (PON1): Subcellular distribution and characterization
9. Stimulation of collagen gene expression by ascorbic acid in cultured human fibroblasts: A role for lipid peroxidation?
10. Relationship between hepatic lipid peroxidation and fibrogenesis in carbon tetrachloride-treated rats: Effect of zinc administration
11. Zinc and iron in free radical pathology and cellular control
12. Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis
13. Preparation and characterisation of microsomal fractions for studies on xenobiotic metabolism
14. The human serum paraoxonase/arylesterase polymorphism
15. Paraoxonase polymorphism Met-Leu 54 is associated with modified serum concentrations of the enzyme
16. Serum paraoxonase and platelet-activating factor acetylhydrolase in chronic renal failure
17. Determination of aldehydic lipid peroxidation products: Malondialdehyde and 4-hydroxynonenal
18. Peroxidation of mullet and rat liver lipids in vitro: Effects of pyridine nucleotides, iron, incubation buffer, and xenobiotics
19. Separation and characterization of the aldehydic products of lipid peroxidation stimulated by carbon tetrachloride or ADP-iron in isolated rat hepatocytes and rat liver microsomal suspensions
20. Time-course of changes in hepatic lipid peroxidation and glutathione metabolism in rats with carbon tetrachloride-induced cirrosis
21. Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions: A possible peroxidative role for paraoxonase
22. Paraoxonase active site required for protection agains LDL oxidation involves its free sulfhydryl group and is different than the required for its arylesterase/paraoxonase activities: Selective action of human paraoxonase alloenzymes Q and R
23. Human serum paraoxonase (PON1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants