The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization

Structure

Volumn 9, Issue 10, 2001, Pages 967-976

  Canals, A ^a   Pous, J ^a  

^a UNIVERSITY OF GIRONA   (Spain)

Author keywords

Domain swapping; Human pancreatic ribonuclease; Molecular evolution; Protein oligomerization; Site directed mutagenesis; X ray crystal structure

Indexed keywords

DIMER; PEPTIDE; RIBONUCLEASE; RIBONUCLEASE PM8; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME SUBUNIT; HUMAN; HYDROGEN BOND; MOLECULAR EVOLUTION; MUTATION; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; CATTLE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; ENDORIBONUCLEASES; ENZYME INHIBITORS; EVOLUTION, MOLECULAR; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDE FRAGMENTS; PLACENTAL HORMONES; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RIBONUCLEASE, PANCREATIC; RIBONUCLEASES;

BOVINAE;

EID: 0034793735     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00659-1     Document Type: Article

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