CTLA-4 gene polymorphism in promoter and exon-1 regions in Chinese patients with systemic lupus erythematosus

Lupus

Volumn 10, Issue 9, 2001, Pages 647-649

  Liu, M F ^a   Wang, C R ^a   Lin, L C ^a   Wu, C R ^a  

^a NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

CTLA 4 gene; Exon 1; Promoter

Indexed keywords

CD28 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4;

ARTICLE; AUTOIMMUNE DISEASE; CHINESE; CLINICAL FEATURE; CONTROLLED STUDY; DNA POLYMORPHISM; EXON; FEMALE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN STRUCTURE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION; ASIAN CONTINENTAL ANCESTRY GROUP; EXONS; GENE FREQUENCY; GENOTYPE; HUMANS; IMMUNOCONJUGATES; LUPUS ERYTHEMATOSUS, SYSTEMIC; PHENOTYPE; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS);

EID: 0034787310     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1191/096120301682430249     Document Type: Article

References (19)

1. CD28/B7 system of T cell costimulation
2. CTLA-4 and CD28 activated lymphocyte molecules are closely related in both mouse and human as to sequence, message expression, gene structure, and chromosomal location
3. CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells
4. CTLA-4 ligation blocks CD28-dependent T cell activation
5. CTLA-4: A negative regulator of autoimmune disease
6. Dinucleotide repeat polymorphism at the human CTLA-4 gene
7. IDDM12 (CTLA-4) on 2q33 and IDDMI3 on 2q34 in genetic susceptibility to type 1 diabetes
8. The CTLA-4 gene region of chromosome 2q33 is linked to and associated with type 1 diabetes
9. A Mse 1 RFLP in the human CTLA-4 promoter
10. CTLA-4 in autoimmune diseases - A general susceptibility gene to autoimmunity?
11. The 1982 revised criteria for the classification of systemic lupus erythematosus
12. Expression of CTLA-4 molecule in peripheral blood T lymphocytes from patients with systemic lupus erythematosus
13. A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus
14. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
15. The A-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus
16. Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus
17. CTLA-4 dimorphism in patients with systemic lupus erythematosus
18. A CTLA-4 polymorphism affects lymphocyte mRNA levels but not associated with type 1 DM in a Canadian dataset
19. CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease