The inhibitory effects of TNP470 on tumour growth of head and neck carcinoma cell producing interleukin-8

Journal of Laryngology and Otology

Volumn 115, Issue 10, 2001, Pages 802-807

  Kawano, Toshirou ^a   Yanoma, Shunsuke ^a   Nishimura, Goshi ^b   Tsukuda, Mamoru ^b  

^a KANAGAWA CANCER CENTER   (Japan)

^b YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Angiogenesis inhibitors; Carcinoma, squamous cell; Head and neck neoplasms; Interleukin 8

Indexed keywords

ANGIOGENESIS INHIBITOR; CYTOKINE ANTIBODY; FUMAGILLOL CHLOROACETYLCARBAMATE; INTERLEUKIN 8; INTERLEUKIN 8 ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; SQUAMOUS CELL CARCINOMA; TUMOR GROWTH; TUMOR VOLUME;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTIBODIES, MONOCLONAL; CARCINOMA, SQUAMOUS CELL; CELL DIVISION; COMBINED MODALITY THERAPY; CYCLOHEXANES; DEPRESSION, CHEMICAL; FLOW CYTOMETRY; HUMANS; INJECTIONS, INTRALESIONAL; INTERLEUKIN-8; MALE; MICE; MICE, NUDE; MOUTH NEOPLASMS; NEOPLASM TRANSPLANTATION; SESQUITERPENES; TUMOR CELLS, CULTURED;

EID: 0034785594     PISSN: 00222151     EISSN: None     Source Type: Journal    
DOI: 10.1258/0022215011909305     Document Type: Article

References (40)

1. Synthetic analogues of fumagillin that inhibit angiogenesis and supress tumour growth
2. Inhibition of tumour growth and metastasis of rodent tumours by the angiogenesis inhibitor o-fumagillol (TNP470;AGM-1470)
3. Inhibitory effect of angiogenesis inhibitor TNP470 on tumour growth and metastasis of human cell lines in vitro and in vivo
4. Antitumour effect of the angiogenesis inhibitor AGM-1470 and its combination effect with tamoxifen in DMBA induced mammary tumours in rats
5. Antitumour effects of angiogenesis inhibitor TNP470 in rabbits bearing VX-2 carcinoma by arterial administration of microspheres and oil solution
6. Intra-tumour injection of an angiogenesis inhibitor, TNP 470, in rabbits bearing VX-2 carcinoma of the tongue
7. Potent antiangiogenic action of AGM-1470: Comparison to the fumagillin parent
8. Suppression of pulmonary metastasis by angiogenesis inhibitor TNP470 in murine osteosarcoma
9. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
10. Interleukin-8 secreted by epithelial cells invaded by bacteria
11. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
12. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis
13. Interleukin-8 as a macrophage derived mediator of angiogenesis
14. Interleukin-8; a corneal factor that induces neovascularization
15. Dual pathways of tubular morphogenesis of vascular endothelial cells by human glioma cells: Vascular endothelial growth factor/basic fibroblast growth factor and interleukin-8
16. Experimental arthritis induced by continuous infusion of IL-8 into rabbit knee joints
17. Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis
18. Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy
19. Chemoattractant and neutrophil degranulation activities related to interleukin-8 in vitreous fluid in uveitis and vitreoretinal disorders
20. Ultraviolet B irradiation promotes tumorgenic and metastatic properties in primary cutaneous melanoma via induction of interleukin-8
21. Role of C-X-C chemokines as regulators of angiogenesis in lung cancer
22. Inhibition of interleukin-8 attenuates angiogenesis in bronchogenic carcinoma
23. Expression of interleukin-8 receptors on tumor cells and vascular endothelial cells in human breast cancer tissue
24. The chemotactic cytokine interleukin-8 A cyst fluid marker for malignant epithelial ovarian cancer
25. Effect of interleukin-8 on production of tumour-associated substances and autocrine growth of human liver and pancreatic cancer cells
26. Expression of interleukin-8 correlates with vascularity in human gastric carcinoma
27. Interleukin-8 inhibits non-small cell lung cancer proliferation. A possible role for regulation of tumour growth by autocrine and paracrine pathways
28. Reversible inhibition of IL-8 receptor B mRNA expression and proliferation in non-small cell lung cancer by antisense oligonucleotides
29. Detection of interleukin-8 mRNA and protein in human colorectal carcinoma cells
30. Interleukine-8 expression by head and neck squamous cell carcinoma
31. Coexpression of interleukin-8 receptors in head and neck squamous cell carcinoma
32. Tumour angiogenesis
33. Inhibition of tumour growth and metastasis of rodent tumours by the angiogenesis inhibitor O-fumagillol (TNP470; AGM-1470)
34. Angiogenesis inhibitor TNP470(AGM-1470) potently inhibits the tumour growth of hormone-independent human breast and prostate carcinoma cell lines
35. Inhibitory effect of angiogenesis inhibitor TNP470 on tumour growth and metastasis of human cell lines in vitro and in vivo
36. Comparison of the inhibitory effect of the angiogenesis inhibitor, TNP470, and mitomycin C on the growth and liver metastasis of human colon cancer
37. Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP470
38. Inhibition of liver metastasis of human gastric carcinoma by angiogenesis inhibitor TNP470
39. Angiogenesis inhibition for the treatment of head and neck cancer
40. AGM-1470, a potent angiogenesis inhibitor, prevents the entry of normal but not transformed endothelial cells into the G1 phase of the cell cycle