Immune responses and latent herpesvirus reactivation in spaceflight

Aviation Space and Environmental Medicine

Volumn 72, Issue 10, 2001, Pages 884-891

  Stowe, R P ^a   Mehta, S K ^a   Ferrando, A A ^a   Feeback, D L ^a   Pierson, D L ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aging; Herpesvirus; Immunity; Microgravity; Spaceflight; Stress

Indexed keywords

CORTICOTROPIN; CYTOMEGALOVIRUS ANTIBODY; HYDROCORTISONE; NEUROHORMONE; PRASTERONE SULFATE; VIRUS ANTIBODY;

ADULT; AGED; ANTIBODY TITER; ARTICLE; BLOOD SAMPLING; CELLULAR IMMUNITY; CLINICAL ARTICLE; COSMONAUT; CYTOMEGALOVIRUS; EPSTEIN BARR VIRUS; HERPES VIRUS; HUMAN; HUMORAL IMMUNITY; LEUKOCYTE COUNT; LYMPHOCYTE SUBPOPULATION; MONOCYTE; NATURAL KILLER CELL; NEUTROPHILIA; SPACE FLIGHT; URINALYSIS; VIRUS LATENCY; VIRUS REACTIVATION;

NASA CENTER JSC; NASA DISCIPLINE REGULATORY PHYSIOLOGY; NON-NASA CENTER;

FLIGHT EXPERIMENT; MANNED; SHORT DURATION; STS-95 SHUTTLE PROJECT;

ADULT; AGE FACTORS; AGED; ANTIBODIES, VIRAL; ASTRONAUTS; CYTOMEGALOVIRUS; DOWN-REGULATION; HERPESVIRIDAE; HUMANS; HYDROCORTISONE; IMMUNITY, CELLULAR; LYMPHOCYTE SUBSETS; MIDDLE AGED; SPACE FLIGHT; STRESS, PSYCHOLOGICAL; VIRUS ACTIVATION; VIRUS LATENCY; VIRUS SHEDDING;

CUCUMBER MOSAIC VIRUS; CYTOMEGALOVIRUS; HERPES; HERPESVIRIDAE; HUMAN HERPESVIRUS 4;

EID: 0034785479     PISSN: 00956562     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (50)

1. Varicella-zoster virus
2. A prospective study of dehydroepiandrosterone sulfate, mortality and cardiovascular disease
3. Adaptation to chronic stress in military trainees. Adrenal androgens, testosterone, glucocorticoids, IGF-1 and immune function
4. Regulation of L-selectin and CD18 on bovine neutrophils by glucocorticoids: Effects of cortisol and dexamethasone
5. Aging, and T-cell-mediated immunity
6. Psychological stress and susceptibility to the common cold
7. Psychological stress, cytokine production, and severity of upper respiratory illness
8. Stress-induced enhancement of antigen-specific cell-mediated immunity
9. A new moderately repetitive DNA sequence family of novel organization
10. Glucocorticosteroid therapy: Mechanisms of action and clinical considerations
11. Modulation, in vivo and in vitro, of surface expression of CD18 by bovine neutrophils
12. Stress, loneliness, and changes in herpesvirus latency
13. Changes in Epstein-Barr virus antibody titers associated with aging
14. Stress-related immune suppression: Health implications
15. Stress-related activation of Epstein-Barr virus
16. Stress and the memory T-cell response to the Epstein-Barr virus in healthy medical students
17. Establishing a pure lymphocyte gate for subset analysis by flow cytometry
18. Psychosocial risk factors in the development of infectious mononucleosis
19. A positive correlation between the precursor frequency of cytotoxic lymphocytes to autologous Epstein-Barr virus-transformed B cells and antibody titer levels against Epstein-Barr virus-associated nuclear antigen in healthy seropositive individuals
20. Unrestricted replication of human cytomegalovirus in hydrocortisone-treated macrophages
21. Regulation of body fluid compartments during short-term spaceflight
22. Academic stress-Influence on Epstein-Barr virus and cytomegalovirus reactivation, cortisol, and prolactin
23. Epstein-Barr virus antibodies in whole blood spots: A minimally invasive method for assessing an aspect of cell-mediated immunity
24. Chronic stress, leukocyte subpopulations, and humoral response to latent viruses
25. Immunologic evidence for frequent age-related cytomegalovirus reactivation in seropositive immunocompetent individuals
26. The role of psychoneuroendocrine factors on spaceflight-induced immunological altertions
27. Reactivation, and shedding of cytomegalovirus in astronauts during spaceflight
28. Androgenic hormones during prolonged physical stress, sleep, and energy deficiency
29. The hypothalamo-pituitary regulation of androgen secretion in young men after prolonged physical stress combined with energy and sleep deprivation
30. The herpesviruses
31. Evidence for adrenocortical adaptation to severe illness
32. Incidence of Epstein-Barr virus in astronaut saliva during spaceflight
33. Modulation of IL-1-induced neutrophil migration by dexamethasone and lipocortin-1
34. Quantitative oropharyngeal Epstein-Barr virus shedding in renal and cardiac transplant recipients: Relationship to immunosuppressive therapy, serologic responses, and the risk of posttransplant lymphoproliferative disorder
35. DHEA-the "mother steroid," I. Immunologic action
36. 24-Hour secretory pattern of dehydroepiandrosterone and dehydroisoandrosterone sulfate
37. Stress and immunity: Implications for viral disease and wound healing
38. Are stressful life events risk factors for herpes zoster
39. Activation of Epstein-Barr virus promoters by a growth-factor and a glucocorticoid
40. Restraint stress differentially affects anti-viral cellular and humoral responses in mice
41. Excretion of IL-6 by astronauts during spaceflight
42. Leukocyte subsets and neutrophil function after short-term spaceflight
43. Stress-induced reactivation of Epstein-Barr virus in astronauts
44. Immunologic analyses of U.S. space shuttle crewmembers
45. In vivo testing confirms a blunting of the human cell-mediated immune mechanism during spaceflight
46. Changes in the immune system during and after spaceflight
47. Antarctic isolation: Immune and viral studies
48. The relationship of serum DHEA-S and cortisol levels to measures of immune function in human immunodeficiency virus-related illness