Advances in understanding the immunopathology of Type 1 diabetes mellitus: Implications for cure and prevention

CPD Bulletin Immunology and Allergy

Volumn 2, Issue 1, 2001, Pages 23-26

  Peakman, M ^a  

^a ST THOMAS HOSPITAL   (United Kingdom)

Author keywords

Autoantibodies; Autoimmune disease; Autoreactive T cells; Glutamic acid decarboxylase; Islet tyrosine phosphatase; Proinsulin; Type 1 diabetes mellitus

Indexed keywords

ANTIGEN; AUTOANTIBODY; AUTOANTIGEN; CORTICOSTEROID DERIVATIVE; CYCLOSPORIN A; GLUTAMATE DECARBOXYLASE; IMMUNOSUPPRESSIVE AGENT; INSULIN; INTERLEUKIN 2 RECEPTOR ANTIBODY; LEUKOCYTE ANTIGEN; PROINSULIN; PROTEIN TYROSINE PHOSPHATASE; TACROLIMUS;

AUTOIMMUNE DISEASE; B LYMPHOCYTE; CHRONIC DISEASE; CLINICAL TRIAL; DEVELOPED COUNTRY; DIABETES MELLITUS; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENVIRONMENTAL FACTOR; FUTUROLOGY; GLUCOSE HOMEOSTASIS; HEALTH PRACTITIONER; HUMAN; IMMUNE DEFICIENCY; IMMUNOLOGY; IMMUNOPATHOLOGY; INCIDENCE; LABORATORY TEST; MASS SCREENING; MEDICAL INFORMATION; MEDICAL RESEARCH; PANCREAS; PANCREAS ISLET TRANSPLANTATION; PATHOGENESIS; PREVENTIVE MEDICINE; REVIEW; T LYMPHOCYTE;

EID: 0034783789     PISSN: 13678949     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (15)

1. Rising incidence of insulin dependent diabetes in children aged under 5 years in the Oxford region: Time trend analysis. The Bart's-Oxford Study Group
2. Report on "the 25th anniversary of the discovery of islet cell antibodies"
3. The World Health Organization International Collaborative Study for islet cell antibodies
4. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay
5. Autoantibodies against recombinant human steroidogenic enzymes 21-hydroxylase, side-chain cleavage and 17alpha-hydroxylase in Addison's disease and autoimmune polyendocrine syndrome type III
6. Optimized autoantibody-based risk assessment in family members. Implications for future intervention trials
7. T cell responses to autoantigens in IDDM
8. Naturally processed and presented epitopes of the islet autoantigen IA-2 eluted from HLA-DR4
9. T-cell markers in type I diabetes: Progress, prospects and realistic expectations
10. Susceptibility to type I diabetes: HLA-DQ and DR revisited
11. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
12. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
13. Twins: Mirrors of the immune system
14. Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: The Finnish Diabetes Prediction and Prevention Study
15. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen