Cuticular collagen synthesis by Ascaris suum during development from the third to fourth larval stage: Identification of a potential chemotherapeutic agent with a novel mechanism of action

Journal of Parasitology

Volumn 87, Issue 5, 2001, Pages 1144-1149

  Rhoads, M L ^a   Fetterer, R H ^a   Urban J F , Jr ^a  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; COLLAGEN; COLLAGENASE; CYSTEINE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DIMER; DITHIOERYTHRITOL; GENE PRODUCT; IODOACETAMIDE; MONOMER; OLIGOMER; PROTOZOAL PROTEIN; THIOL GROUP;

PARASITOLOGY;

ARTICLE; ASCARIS SUUM; COLLAGEN DEGRADATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; CROSS LINKING; CUTICLE; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG PROTEIN BINDING; LARVAL DEVELOPMENT; MOLTING; NONHUMAN; PARASITE CONTROL; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PROTEIN SECRETION; REDUCTION; RNA TRANSLATION; SEQUENCE ANALYSIS;

ASCARIS SUUM; NEMATODA;

EID: 0034773596     PISSN: 00223395     EISSN: None     Source Type: Journal    
DOI: 10.1645/0022-3395(2001)087[1144:ccsbas]2.0.co;2     Document Type: Article

References (26)

1. Analysis of the cuticular collagens of Ascaris suum
2. Molecular biology of the cuticle collagen gene families of Caenorhabditis elegans and Haemonchus contortus
3. Molecular and biochemical aspects of nematode collagens
4. Growth and cuticular synthesis in Ascaris suum larvae during development from the third to fourth stage in vitro
5. Tyrosine-derived cross-linking amino acids in the sheath of Haemonchus contortus infective larvae
6. Synthesis of tyrosine-derived cross-links in Ascaris suum cuticular proteins
7. The inhibition of growth and development of Ascaris suum larvae in vitro by proline analogs
8. Developmental changes in cuticular proteins of Ascaris suum.
9. Effects of the chitin synthesis inhibitor diflubenzuron on development of Ascaris suum and Haemonchus contortus
10. Ascaris suum: Role of ecdysteroids in molting
11. Isotrityrosine, a new cross-linking amino acid isolated from Ascaris cuticle collagen
12. The cuticle of the nematode Caenorhabditis elegans: A complex collagen structure
13. Nematode collagen genes
14. Comparison of collagen gene sequences in Ascaris suum and Caenorhabditis elegans
15. Structures and functions of collagens in Caenorhabditis elegans
16. Comparisons of the complete sequences of two collagen genes from Caenorhabditis elegans
17. Caenorhabditis elegans as a model for parasitic nematodes: A focus on the cuticle
18. Selective activation of caspases during apoptotic induction in HL-60 cells
19. Secretion of an aminopeptidase during transition of third- to fourth-stage larvae of Ascaris suum
20. Effect of protease class-specific inhibitors on in vitro development of the third- to fourth-stage larvae of Arcaris suum
21. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates
22. Cuticle collagen genes of Haemonchus contortus and Caenorhabditis elegans are highly conserved
23. Cysteinyl proteinases and their selective inactivation
24. In vitro development of Ascaris suum from third- to fourth-stage larvae and detection of metabolic antigens in multi-well culture systems
25. The synthesis, kinetic characterization and application of a novel biotinylated affinity label for cathepsin B
26. Proteolytic processing of Caenorhabditis elegans SQT-1 cuticle collagen is inhibited in right roller mutants whereas cross-linking is inhibited in left roller mutants