Identification and characterization of the hemophore-dependent heme acquisition system of Yersinia pestis

Infection and Immunity

Volumn 69, Issue 11, 2001, Pages 6707-6717

  Rossi, M S ^a   Fetherston, J D ^a   Letoffe S ^a   Carniel, E ^a   Perry, R D ^a   Ghigo, J M ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; BINDING PROTEIN; HEME; HEMOGLOBIN; HEMOPROTEIN; IRON; PROTEIN HASA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL VIRULENCE; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; SERRATIA MARCESCENS; YERSINIA PESTIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CARRIER PROTEINS; CULTURE MEDIA; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; HEME; HEMEPROTEINS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; MUTAGENESIS; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TEMPERATURE; VIRULENCE; YERSINIA PESTIS;

EID: 0034773143     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.11.6707-6717.2001     Document Type: Article

References (44)

1. Lipase secretion by bacterial hybrid ATP-binding cassette exporters: Molecular recognition of the LipBCD, PrtDEF, and HasDEF exporters
2. The Yfe system of Yersinia pestis transports iron and manganese and is required for full virulence of plague
3. Assessment of a fluoroquinolone, three β-1actams, two aminoglycosides, and a cycline in treatment of murine Yersinia pestis infection
4. Surface signaling: Novel transcription initiation mechanism starting from the cell surface
5. Bacterial iron transport: Mechanisms, genetics, and regulation
6. The Yersinia high-pathogenicity island
7. Chromosomal marker for the 'high pathogenicity' phenotype in Yersinia
8. Expression of iron-regulated proteins in Yersinia species and their relation to virulence
9. Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid
10. Analysis of the pesticin receptor from Yersinia pestis: Role in iron-deficient growth and possible regulation by its siderophore
11. Regulation of ms, a positive regulatory factor for pili of enterotoxigenic Escherichia coli
12. A new type of hemophore-dependent heme acquisition system of Serratia marcescens reconstituted in Escherichia coli
13. Characterization of the Yersinia pestis Yfu ABC inorganic iron transport system
14. The iron-uptake systems of pathogenic bacteria
15. Virulence of Yersinia enterocolitica is closely associated with siderophore production, expression of an iron-repressible outer membrane polypeptide of 65,000 Da and pesticin sensitivity
16. Using CLUSTAL for multiple sequence alignments
17. The hmu locus of Yersinia pestis is essential for utilization of free haemin and haem-protein complexes as iron sources
18. A wide-host-range suicide vector for improving reverse genetics in gram-negative bacteria: Inactivation of the blaA gene of Yersinia enterocolitica
19. Transcription induction of the ferric citrate transport genes via the N-terminus of the FecA outer membrane protein, the Ton system and the electrochemical potential of the cytoplasmic membrane
20. Temperature-regulated expression of bacterial virulence genes
21. Iron acquisition from heme and hemoglobin by a Serratia marcescens extracellular protein
22. Secretion of the Serratia marcescens HasA protein by an ABC transporter
23. Interactions of HasA, a bacterial haemophore, with haemoglobin and with its outer membrane receptor HasR
24. PF hemophore and its truncated and chimeric variants: Determination of a region involved in binding to the hemophore receptor
25. Isolation and characterization of an extracellular haem-binding protein from Pseudomonas aerugiosa that shares function and sequence similarities with the Serratia marcescens HasA haemophore
26. 'DNA Strider': A 'C' program for the fast analysis of DNA and protein sequences on the Apple Macintosh family of computers
27. The role of iron-binding proteins in the survival of pathogenic bacteria
28. Genetics and regulation of two distinct haem-uptake systems, phu and has, in Pseudomonas aeruginosa
29. Characterisation of HasB, a Serratia marcescens TonB-like protein specifically involved in the hemophore-dependent heme acquisition system
30. Identification and cloning of a hemin storage locus involved in the pigmentation phenotype of Yersinia pestis
31. Iron and heme acquisition storage systems in Yersinia pestis
32. A simple method of estimating fifty percent endpoints
33. DNA sequencing with chain-terminating inhibitors
34. Silencing and reactivation of urease in Yersinia pestis is determined by one G residue at a specific position in the ureD gene
35. Kanamycin-resistant vectors that are analogues of plasmids pUC8, pUC9, pEMBL8 and pEMBL9
36. Pleiotropic effects of a Yersinia pestis fur mutation
37. Identification and cloning of a fur regulatory gene in Yersinia pestis
38. Fur regulon in gram-negative bacteria. Identification and characterization of new iron-regulated Escherichia coli genes by a fur titration assay
39. Hemin uptake system of Yersinia enterocolitica: Similarities with other TonB-dependent systems in gram-negative bacteria
40. Versatile low-copy-number plasmid vectors for cloning in Escherichia coli
41. Molecular characterization of the hemin uptake locus (hmu) from Yersinia pestis and analysis of hmu mutants for hemin and hemoprotein utilization
42. Bacterial heme sources: The role of heme, hemoprotein receptors and hemophores