Bacitracin inhibits fibronectin matrix assembly by mesangial cells in high glucose

Kidney International

Volumn 60, Issue 5, 2001, Pages 1756-1764

  Weston, Benjamin S ^a   Wahab, Nadia Abdel ^a   Roberts, Terry ^a   Mason, Roger M ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Antibiotic; Diabetic nephropathy; End stage renal disease; Extracellular matrix; Glycoprotein; Protein disulfide isomerase

Indexed keywords

BACITRACIN; FIBRONECTIN; GLUCOSE; LEUCINE; MESSENGER RNA; PROTEIN DISULFIDE ISOMERASE; TRITIUM;

ARTICLE; CELL CULTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IMMUNOHISTOLOGY; ISOTOPE LABELING; MESANGIUM CELL; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034773112     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.00991.x     Document Type: Article

References (46)

1. Clinical features and epidemiology of diabetic nephropathy
2. Pathogenesis of nephropathy
3. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
4. Interaction of ascorbic acid and glucose on the production of collagen and proteoglycan by fibroblasts
5. Characterization of proteoglycans synthesized by human adult glomerular mesangial cells in culture
6. Mechanisms of glucose enhanced extracellular matrix accumulation in rat glomerular mesangial cells
7. Immunohistochemical localization of extracellular-matrix components in human diabetic glomerular lesions
8. Increased extracellular-matrix synthesis in mesangial cells grown in high-glucose medium
9. Expression of extracellular matrix molecules in human mesangial cells in response to prolonged hyperglycaemia
10. Modulation of neural protease expression in human mesangial cells by hyperglycaemic culture
11. The role of the mesangial cell and its matrix in the pathogenesis of diabetic nephropathy
12. Fibronectin
13. Fibronectin fibrillogenesis: A paradigm for extracellular matrix assembly
14. Assembly of fibronectin into an insoluble matrix
15. Identification of protein-disulphide isomerase activity in fibronectin
16. Distribution of the extracellular-matrix components in human glomerular-lesions
17. Familial glomerulo-nephritis characterized by massive deposits of fibronectin
18. Glomerulopathy associated with predominant fibronectin-deposits - A newly recognized hereditary disease
19. Bacitracin: An inhibitor of the insulin degrading activity of glutathione-insulin dehydrogenase
20. Purification and characterisation of yeast protein disulfide isomerase
21. Protein disulphide isomerase mediates platelet aggregation and secretion
22. Secretion, surface localisation, turnover and steady state expression of protein disulphide isomerase in rat hepatocytes
23. Inhibition of human immunodeficiency virus infection by agents that interfere with thiol-disulfide interchange upon virus-receptor interaction
24. Inhibition of the reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase
25. Enzyme destruction by a protease contaminant in bacitracin
26. Rapid methods for isolation of human plasma fibronectin
27. Fibronectin augments monocyte adhesion to low-density lipoprotein-stimulated mesangial cells
28. Fibronectin's amino-terminal matrix assembly site is located within the 29-kDa amino-terminal domain containing five type I repeats
29. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
30. Single step methods of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
31. Suppression subtractive hybridisation identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells
32. Cytotoxicity to cultured human keratinocytes of topical antimicrobial reagents
33. Toxic effects of wound irrigation solutions on cultured tibiae and osteoblasts
34. 7 integrin-mediated lymphocyte adhesion by bacitracin
35. Formation of sodium dodecyl sulfate-stable fibronectin multimers. Failure to detect products of thiol-disulfide exchange in cyanogen bromide or limited acid digests of stabilized matrix fibronectin
36. Fibronectin structure and assembly
37. Dynamics and elasticity of the fibronectin matrix in living cell culture visualised by fibronectin-green fluorescent protein
38. 13
39. 3 has an endogenous thiol isomerase activity
40. Adhesion molecules in the glomerular mesangium
41. Neutralisation of TGF-beta by anti-TGF-beta antibodies attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice
42. Inhibiting albumin glycation ameliorates diabetic nephropathy in the db/db mouse
43. Lovastatin inhibits transforming growth factor-β1 expression in diabetic rat glomeruli and cultured rat mesangial cells
44. Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC β inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
45. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal anti-transforming growth factor-β antibody in db/db diabetic mice
46. Thrombospondin-1 is the key activator of TGF-β1 in human mesangial cells exposed to high glucose