Regulation of E-box DNA binding during in vivo and in vitro activation of rat and human hepatic stellate cells

Gut

Volumn 49, Issue 5, 2001, Pages 713-719

  Vincent, K J ^a   Jones, E ^a   Arthur, M J P ^a   Smart, D E ^a   Trim, J ^a   Wright, M C ^a   Mann, D A ^a  

^a SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

Author keywords

Basic helix loop helix transcription factors; Hepatic stellate cell; Id1; Liver fibrosis; MyoD

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; CARBON TETRACHLORIDE; DNA; E BOX TRANSCRIPTION FACTOR; HELIX LOOP HELIX PROTEIN; HOMEODOMAIN PROTEIN; INHIBITOR OF DIFFERENTIATION 1; MESSENGER RNA; MYOD PROTEIN; MYOSIN ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DNA BINDING; DNA SEQUENCE; FIBROGENESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; LIVER CELL; LIVER TOXICITY; MALE; MYOFIBROBLAST; NONHUMAN; NORTHERN BLOTTING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; RAT; STELLATE CELL; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ADULT; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CARBON TETRACHLORIDE; CELL DIFFERENTIATION; CELLS, CULTURED; DNA-BINDING PROTEINS; E-BOX ELEMENTS; HELIX-LOOP-HELIX MOTIFS; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; LIVER; MALE; MYOD PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; REPRESSOR PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 0034771455     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.49.5.713     Document Type: Article

References (36)

1. The cellular basis of hepatic fibrosis
2. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
3. Hepatic stellate (ITO) cells: Expanding roles for a liver-specific pericyte
4. The role of fat-storing cells in Disse space fibrogenesis in alcoholic liver disease
5. Hepatic fibrosis as wound repair: A progress report
6. Control of the tissue inhibitor of metalloproteinases-1 promoter in culture activated rat hepatic stellate cells: Regulation by activator protein-1 DNA binding proteins
7. Persistent expression of nuclear factor-κB in cultured rat hepatic stellate cells involves the induction of potentially novel rel-like factors and prolonged changes in the expression of IκB family proteins
8. HLH proteins, fly neurogenesis, and vertebrate myogenesis
9. The MyoD family and myogenesis: Redundancy, networks, and thresholds
10. bHLH factors in muscle development: Dead lines and commitments, what to leave in and what to leave out
11. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection
12. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence
13. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo
14. Localisation of E2A mRNA expression in developing and adult rat tissues
15. The protein Id: A negative regulator of helix-loop-helix DNA binding proteins
16. Human hepatic lipocytes synthesise tissue inhibitor of metalloproteinases-1
17. Mechanisms of spontaneous resolution of rat liver fibrosis - Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
18. Determination of the c-Myc DNA-binding site
19. Rat hepatic stellate lipocytes express smooth muscle actin upon activation in vivo and in culture
20. Hypermethylated myoblasts specifically deficient in MyoD autoactivation as a consequence of instability of MyoD
21. Induction of activator protein-1 (AP-1) in macrophages by human immunodeficiency virus type-1 Nef is a cell-type-specific response that requires both Hck and MAPK signaling events
22. Expression of a single transfected cDNA converts fibroblasts into myoblasts
23. Sarcomeric gene expression and contractility in myofibroblasts
24. Immunocytochemical detection of desmin in fat-storing cells (Ito cells)
25. Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells
26. Expression of myogenic regulatory proteins (Myogenin and MyoD 1) in small blue round cell tumors of childhood
27. Activation of hepatic stellate cells by TGF alpha and collagen type 1 is mediated by oxidative stress through c-myb expression
28. Platelet-derived growth factor is a principle inductive factor modulating mannose 6-phosphate/insulin-like growth factor-II receptor gene expression via a distal E-box in activated hepatic stellate cells
29. c-Myc target gene specificity is determined by a post-DNA binding mechanism
30. An E-box-mediated increase in cad transcription at G1/S-phase boundary is supposed by inhibitory c-Myc mutants
31. An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins
32. IB-, a novel member of the IB family, controls RelA and cRel NF-B activity
33. Molecular and functional properties of the human α (1G) subunit that forms T-type calcium channels
34. Degradation of myogenic transcription factor MyoD by the ubiquitin pathway in vivo and in vitro: Regulation by specific DNA binding
35. Degradation of Id proteins by the ubiquitin-proteasome pathway
36. Differential interactions of Id proteins with Basic-Helix-Loop-Helix transcription factors